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Relaxed specificity of matrix metalloproteinases (MMPS) and TIMP insensitivity of tumor necrosis factor-alpha (TNF-alpha) production suggest the major TNF-alpha converting enzyme is not an MMP.
Black RA, Durie FH, Otten-Evans C, Miller R, Slack JL, Lynch DH, Castner B, Mohler KM, Gerhart M, Johnson RS, Itoh Y, Okada Y, Nagase H. Black RA, et al. Among authors: otten evans c. Biochem Biophys Res Commun. 1996 Aug 14;225(2):400-5. doi: 10.1006/bbrc.1996.1186. Biochem Biophys Res Commun. 1996. PMID: 8753775