von Figura K - Search Results

1

Mice deficient for the lysosomal proteinase cathepsin D exhibit progressive atrophy of the intestinal mucosa and profound destruction of lymphoid cells.

Saftig P, Hetman M, Schmahl W, Weber K, Heine L, Mossmann H, Köster A, Hess B, Evers M, von Figura K, et al. Saftig P, et al. Among authors: von figura k. EMBO J. 1995 Aug 1;14(15):3599-608. doi: 10.1002/j.1460-2075.1995.tb00029.x. EMBO J. 1995. PMID: 7641679 Free PMC article.

2

Targeted disruption of the M(r) 46,000 mannose 6-phosphate receptor gene in mice results in misrouting of lysosomal proteins.

Köster A, Saftig P, Matzner U, von Figura K, Peters C, Pohlmann R. Köster A, et al. Among authors: von figura k. EMBO J. 1993 Dec 15;12(13):5219-23. doi: 10.1002/j.1460-2075.1993.tb06217.x. EMBO J. 1993. PMID: 8262064 Free PMC article.

3

Mistargeting of lysosomal enzymes in M(r) 46,000 mannose 6-phosphate receptor-deficient mice is compensated by carbohydrate-specific endocytotic receptors.

Köster A, von Figura K, Pohlmann R. Köster A, et al. Among authors: von figura k. Eur J Biochem. 1994 Sep 1;224(2):685-9. doi: 10.1111/j.1432-1033.1994.00685.x. Eur J Biochem. 1994. PMID: 7925385 Free article.

Targeted disruption of the M(r) 46,000 mannose 6-phosphate receptor (MPR 46) in mice is associated with normal levels of lysosomal enzymes in the circulation, while in MPR 46-deficient cells an increased secretion of lysosomal enzymes is apparent [Koster, A., Saftig, P., Matzner, …

Targeted disruption of the M(r) 46,000 mannose 6-phosphate receptor (MPR 46) in mice is associated with normal levels of lysosomal enzymes i …

4

Targeted disruption of the arylsulfatase B gene results in mice resembling the phenotype of mucopolysaccharidosis VI.

Evers M, Saftig P, Schmidt P, Hafner A, McLoghlin DB, Schmahl W, Hess B, von Figura K, Peters C. Evers M, et al. Among authors: von figura k. Proc Natl Acad Sci U S A. 1996 Aug 6;93(16):8214-9. doi: 10.1073/pnas.93.16.8214. Proc Natl Acad Sci U S A. 1996. PMID: 8710849 Free PMC article.

5

Proteolysis of IGFBPs by cathepsin D in vitro and in cathepsin D-deficient mice.

Braulke T, Claussen M, Saftig P, Wendland M, Neifer K, Schmidt B, Zapf J, von Figura K, Peters C. Braulke T, et al. Among authors: von figura k. Prog Growth Factor Res. 1995;6(2-4):265-71. doi: 10.1016/0955-2235(95)00005-4. Prog Growth Factor Res. 1995. PMID: 8817669 Review.

6

Phenotype of arylsulfatase A-deficient mice: relationship to human metachromatic leukodystrophy.

Hess B, Saftig P, Hartmann D, Coenen R, Lüllmann-Rauch R, Goebel HH, Evers M, von Figura K, D'Hooge R, Nagels G, De Deyn P, Peters C, Gieselmann V. Hess B, et al. Among authors: von figura k. Proc Natl Acad Sci U S A. 1996 Dec 10;93(25):14821-6. doi: 10.1073/pnas.93.25.14821. Proc Natl Acad Sci U S A. 1996. PMID: 8962139 Free PMC article.

7

Mice deficient in lysosomal acid phosphatase develop lysosomal storage in the kidney and central nervous system.

Saftig P, Hartmann D, Lüllmann-Rauch R, Wolff J, Evers M, Köster A, Hetman M, von Figura K, Peters C. Saftig P, et al. Among authors: von figura k. J Biol Chem. 1997 Jul 25;272(30):18628-35. doi: 10.1074/jbc.272.30.18628. J Biol Chem. 1997. PMID: 9228031 Free article.

8

Alternative mechanisms for trafficking of lysosomal enzymes in mannose 6-phosphate receptor-deficient mice are cell type-specific.

Dittmer F, Ulbrich EJ, Hafner A, Schmahl W, Meister T, Pohlmann R, von Figura K. Dittmer F, et al. Among authors: von figura k. J Cell Sci. 1999 May;112 ( Pt 10):1591-7. doi: 10.1242/jcs.112.10.1591. J Cell Sci. 1999. PMID: 10212152

9

Normal lysosomal morphology and function in LAMP-1-deficient mice.

Andrejewski N, Punnonen EL, Guhde G, Tanaka Y, Lüllmann-Rauch R, Hartmann D, von Figura K, Saftig P. Andrejewski N, et al. Among authors: von figura k. J Biol Chem. 1999 Apr 30;274(18):12692-701. doi: 10.1074/jbc.274.18.12692. J Biol Chem. 1999. PMID: 10212251 Free article.

10

mu1A-adaptin-deficient mice: lethality, loss of AP-1 binding and rerouting of mannose 6-phosphate receptors.

Meyer C, Zizioli D, Lausmann S, Eskelinen EL, Hamann J, Saftig P, von Figura K, Schu P. Meyer C, et al. Among authors: von figura k. EMBO J. 2000 May 15;19(10):2193-203. doi: 10.1093/emboj/19.10.2193. EMBO J. 2000. PMID: 10811610 Free PMC article.

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