Kotian P - Search Results

1

Synthesis and ligand binding study of 3 beta-(4'-substituted phenyl)-2 beta-(heterocyclic)tropanes.

Kotian P, Abraham P, Lewin AH, Mascarella SW, Boja JW, Kuhar MJ, Carroll FI. Kotian P, et al. J Med Chem. 1995 Sep 1;38(18):3451-3. doi: 10.1021/jm00018a004. J Med Chem. 1995. PMID: 7658431 No abstract available.

2

Cocaine and 3 beta-(4'-substituted phenyl)tropane-2 beta-carboxylic acid ester and amide analogues. New high-affinity and selective compounds for the dopamine transporter.

Carroll FI, Kotian P, Dehghani A, Gray JL, Kuzemko MA, Parham KA, Abraham P, Lewin AH, Boja JW, Kuhar MJ. Carroll FI, et al. Among authors: kotian p. J Med Chem. 1995 Jan 20;38(2):379-88. doi: 10.1021/jm00002a020. J Med Chem. 1995. PMID: 7830281

3

Synthesis, ligand binding, and quantitative structure-activity relationship study of 3 beta-(4'-substituted phenyl)-2 beta-heterocyclic tropanes: evidence for an electrostatic interaction at the 2 beta-position.

Kotian P, Mascarella SW, Abraham P, Lewin AH, Boja JW, Kuhar MJ, Carroll FI. Kotian P, et al. J Med Chem. 1996 Jul 5;39(14):2753-63. doi: 10.1021/jm960160e. J Med Chem. 1996. PMID: 8709106

4

Synthesis and nicotinic acetylcholine receptor binding properties of exo-2-(2'-fluoro-5'-pyridinyl)-7-azabicyclo-[2.2.1]heptane: a new positron emission tomography ligand for nicotinic receptors.

Liang F, Navarro HA, Abraham P, Kotian P, Ding YS, Fowler J, Volkow N, Kuhar MJ, Carroll FI. Liang F, et al. Among authors: kotian p. J Med Chem. 1997 Jul 18;40(15):2293-5. doi: 10.1021/jm970187d. J Med Chem. 1997. PMID: 9240344 No abstract available.

5

Design and synthesis of benzoic acid derivatives as influenza neuraminidase inhibitors using structure-based drug design.

Chand P, Babu YS, Bantia S, Chu N, Cole LB, Kotian PL, Laver WG, Montgomery JA, Pathak VP, Petty SL, Shrout DP, Walsh DA, Walsh GM. Chand P, et al. Among authors: kotian pl. J Med Chem. 1997 Dec 5;40(25):4030-52. doi: 10.1021/jm970479e. J Med Chem. 1997. PMID: 9406595

6

BCX-1812 (RWJ-270201): discovery of a novel, highly potent, orally active, and selective influenza neuraminidase inhibitor through structure-based drug design.

Babu YS, Chand P, Bantia S, Kotian P, Dehghani A, El-Kattan Y, Lin TH, Hutchison TL, Elliott AJ, Parker CD, Ananth SL, Horn LL, Laver GW, Montgomery JA. Babu YS, et al. Among authors: kotian p. J Med Chem. 2000 Sep 21;43(19):3482-6. doi: 10.1021/jm0002679. J Med Chem. 2000. PMID: 11000002 No abstract available.

7

Systematic structure-based design and stereoselective synthesis of novel multisubstituted cyclopentane derivatives with potent antiinfluenza activity.

Chand P, Kotian PL, Dehghani A, El-Kattan Y, Lin TH, Hutchison TL, Babu YS, Bantia S, Elliott AJ, Montgomery JA. Chand P, et al. Among authors: kotian pl. J Med Chem. 2001 Dec 6;44(25):4379-92. doi: 10.1021/jm010277p. J Med Chem. 2001. PMID: 11728184

8

Synthesis and inhibitory activity of benzoic acid and pyridine derivatives on influenza neuraminidase.

Chand P, Kotian PL, Morris PE, Bantia S, Walsh DA, Babu YS. Chand P, et al. Among authors: kotian pl. Bioorg Med Chem. 2005 Apr 1;13(7):2665-78. doi: 10.1016/j.bmc.2005.01.042. Bioorg Med Chem. 2005. PMID: 15755666

9

Syntheses and neuraminidase inhibitory activity of multisubstituted cyclopentane amide derivatives.

Chand P, Babu YS, Bantia S, Rowland S, Dehghani A, Kotian PL, Hutchison TL, Ali S, Brouillette W, El-Kattan Y, Lin TH. Chand P, et al. Among authors: kotian pl. J Med Chem. 2004 Apr 8;47(8):1919-29. doi: 10.1021/jm0303406. J Med Chem. 2004. PMID: 15055992

10

Comparison of the anti-influenza virus activity of cyclopentane derivatives with oseltamivir and zanamivir in vivo.

Chand P, Bantia S, Kotian PL, El-Kattan Y, Lin TH, Babu YS. Chand P, et al. Among authors: kotian pl. Bioorg Med Chem. 2005 Jun 2;13(12):4071-7. doi: 10.1016/j.bmc.2005.03.048. Epub 2005 Apr 25. Bioorg Med Chem. 2005. PMID: 15911320

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