Fajardo JE - Search Results

1

Identification and characterization of a high-affinity interaction between v-Crk and tyrosine-phosphorylated paxillin in CT10-transformed fibroblasts.

Birge RB, Fajardo JE, Reichman C, Shoelson SE, Songyang Z, Cantley LC, Hanafusa H. Birge RB, et al. Among authors: fajardo je. Mol Cell Biol. 1993 Aug;13(8):4648-56. doi: 10.1128/mcb.13.8.4648-4656.1993. Mol Cell Biol. 1993. PMID: 7687742 Free PMC article.

2

The SH2- and SH3-containing Nck protein transforms mammalian fibroblasts in the absence of elevated phosphotyrosine levels.

Chou MM, Fajardo JE, Hanafusa H. Chou MM, et al. Among authors: fajardo je. Mol Cell Biol. 1992 Dec;12(12):5834-42. doi: 10.1128/mcb.12.12.5834-5842.1992. Mol Cell Biol. 1992. PMID: 1280326 Free PMC article.

3

Tyrosine-phosphorylated epidermal growth factor receptor and cellular p130 provide high affinity binding substrates to analyze Crk-phosphotyrosine-dependent interactions in vitro.

Birge RB, Fajardo JE, Mayer BJ, Hanafusa H. Birge RB, et al. Among authors: fajardo je. J Biol Chem. 1992 May 25;267(15):10588-95. J Biol Chem. 1992. PMID: 1375224 Free article.

4

A 31-amino-acid N-terminal extension regulates c-Crk binding to tyrosine-phosphorylated proteins.

Fajardo JE, Birge RB, Hanafusa H. Fajardo JE, et al. Mol Cell Biol. 1993 Dec;13(12):7295-302. doi: 10.1128/mcb.13.12.7295-7302.1993. Mol Cell Biol. 1993. PMID: 7504172 Free PMC article.

5

Expression of the v-crk oncogene product in PC12 cells results in rapid differentiation by both nerve growth factor- and epidermal growth factor-dependent pathways.

Hempstead BL, Birge RB, Fajardo JE, Glassman R, Mahadeo D, Kraemer R, Hanafusa H. Hempstead BL, et al. Among authors: fajardo je. Mol Cell Biol. 1994 Mar;14(3):1964-71. doi: 10.1128/mcb.14.3.1964-1971.1994. Mol Cell Biol. 1994. PMID: 7509449 Free PMC article.

6

Crk at the quarter century mark: perspectives in signaling and cancer.

Kumar S, Fajardo JE, Birge RB, Sriram G. Kumar S, et al. Among authors: fajardo je. J Cell Biochem. 2014 May;115(5):819-25. doi: 10.1002/jcb.24749. J Cell Biochem. 2014. PMID: 24356912

7

v-Crk modulation of growth factor-induced PC12 cell differentiation involves the Src homology 2 domain of v-Crk and sustained activation of the Ras/mitogen-activated protein kinase pathway.

Teng KK, Lander H, Fajardo JE, Hanafusa H, Hempstead BL, Birge RB. Teng KK, et al. Among authors: fajardo je. J Biol Chem. 1995 Sep 1;270(35):20677-85. doi: 10.1074/jbc.270.35.20677. J Biol Chem. 1995. PMID: 7657647 Free article.

8

Phosphorylation of c-Crk II on the negative regulatory Tyr222 mediates nerve growth factor-induced cell spreading and morphogenesis.

Escalante M, Courtney J, Chin WG, Teng KK, Kim JI, Fajardo JE, Mayer BJ, Hempstead BL, Birge RB. Escalante M, et al. Among authors: fajardo je. J Biol Chem. 2000 Aug 11;275(32):24787-97. doi: 10.1074/jbc.M000711200. J Biol Chem. 2000. PMID: 10825157 Free article.

9

Activation of the focal adhesion kinase signaling pathway by structural alterations in the carboxyl-terminal region of c-Crk II.

Zvara A, Fajardo JE, Escalante M, Cotton G, Muir T, Kirsch KH, Birge RB. Zvara A, et al. Among authors: fajardo je. Oncogene. 2001 Feb 22;20(8):951-61. doi: 10.1038/sj.onc.1204173. Oncogene. 2001. PMID: 11314030

10

Transactivation of Abl by the Crk II adapter protein requires a PNAY sequence in the Crk C-terminal SH3 domain.

Reichman C, Singh K, Liu Y, Singh S, Li H, Fajardo JE, Fiser A, Birge RB. Reichman C, et al. Among authors: fajardo je. Oncogene. 2005 Dec 8;24(55):8187-99. doi: 10.1038/sj.onc.1208988. Oncogene. 2005. PMID: 16158059

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