Paielli D - Search Results

1

Identification of tissue-type plasminogen activator-specific plasminogen activator inhibitor-1 mutants. Evidence that second sites of interaction contribute to target specificity.

Sherman PM, Lawrence DA, Verhamme IM, Paielli D, Shore JD, Ginsburg D. Sherman PM, et al. Among authors: paielli d. J Biol Chem. 1995 Apr 21;270(16):9301-6. doi: 10.1074/jbc.270.16.9301. J Biol Chem. 1995. PMID: 7721851 Free article.

2

Saturation mutagenesis of the plasminogen activator inhibitor-1 reactive center.

Sherman PM, Lawrence DA, Yang AY, Vandenberg ET, Paielli D, Olson ST, Shore JD, Ginsburg D. Sherman PM, et al. Among authors: paielli d. J Biol Chem. 1992 Apr 15;267(11):7588-95. J Biol Chem. 1992. PMID: 1559996 Free article.

3

In vivo antitumor activity of ONYX-015 is influenced by p53 status and is augmented by radiotherapy.

Rogulski KR, Freytag SO, Zhang K, Gilbert JD, Paielli DL, Kim JH, Heise CC, Kirn DH. Rogulski KR, et al. Among authors: paielli dl. Cancer Res. 2000 Mar 1;60(5):1193-6. Cancer Res. 2000. PMID: 10728673

4

Phase I study of replication-competent adenovirus-mediated double suicide gene therapy for the treatment of locally recurrent prostate cancer.

Freytag SO, Khil M, Stricker H, Peabody J, Menon M, DePeralta-Venturina M, Nafziger D, Pegg J, Paielli D, Brown S, Barton K, Lu M, Aguilar-Cordova E, Kim JH. Freytag SO, et al. Among authors: paielli d. Cancer Res. 2002 Sep 1;62(17):4968-76. Cancer Res. 2002. PMID: 12208748 Clinical Trial.

5

A novel three-pronged approach to kill cancer cells selectively: concomitant viral, double suicide gene, and radiotherapy.

Freytag SO, Rogulski KR, Paielli DL, Gilbert JD, Kim JH. Freytag SO, et al. Among authors: paielli dl. Hum Gene Ther. 1998 Jun 10;9(9):1323-33. doi: 10.1089/hum.1998.9.9-1323. Hum Gene Ther. 1998. PMID: 9650617

6

Double suicide gene therapy augments the antitumor activity of a replication-competent lytic adenovirus through enhanced cytotoxicity and radiosensitization.

Rogulski KR, Wing MS, Paielli DL, Gilbert JD, Kim JH, Freytag SO. Rogulski KR, et al. Among authors: paielli dl. Hum Gene Ther. 2000 Jan 1;11(1):67-76. doi: 10.1089/10430340050016166. Hum Gene Ther. 2000. PMID: 10646640

7

Efficacy and toxicity of replication-competent adenovirus-mediated double suicide gene therapy in combination with radiation therapy in an orthotopic mouse prostate cancer model.

Freytag SO, Paielli D, Wing M, Rogulski K, Brown S, Kolozsvary A, Seely J, Barton K, Dragovic A, Kim JH. Freytag SO, et al. Among authors: paielli d. Int J Radiat Oncol Biol Phys. 2002 Nov 1;54(3):873-85. doi: 10.1016/s0360-3016(02)03005-5. Int J Radiat Oncol Biol Phys. 2002. PMID: 12377341

8

Phase I study of replication-competent adenovirus-mediated double-suicide gene therapy in combination with conventional-dose three-dimensional conformal radiation therapy for the treatment of newly diagnosed, intermediate- to high-risk prostate cancer.

Freytag SO, Stricker H, Pegg J, Paielli D, Pradhan DG, Peabody J, DePeralta-Venturina M, Xia X, Brown S, Lu M, Kim JH. Freytag SO, et al. Among authors: paielli d. Cancer Res. 2003 Nov 1;63(21):7497-506. Cancer Res. 2003. PMID: 14612551 Clinical Trial.

9

Second-generation replication-competent oncolytic adenovirus armed with improved suicide genes and ADP gene demonstrates greater efficacy without increased toxicity.

Barton KN, Paielli D, Zhang Y, Koul S, Brown SL, Lu M, Seely J, Kim JH, Freytag SO. Barton KN, et al. Among authors: paielli d. Mol Ther. 2006 Feb;13(2):347-56. doi: 10.1016/j.ymthe.2005.10.005. Epub 2005 Nov 14. Mol Ther. 2006. PMID: 16290236 Free article.

10

Evaluation of the biodistribution, persistence, toxicity, and potential of germ-line transmission of a replication-competent human adenovirus following intraprostatic administration in the mouse.

Paielli DL, Wing MS, Rogulski KR, Gilbert JD, Kolozsvary A, Kim JH, Hughes J, Schnell M, Thompson T, Freytag SO. Paielli DL, et al. Mol Ther. 2000 Mar;1(3):263-74. doi: 10.1006/mthe.2000.0037. Mol Ther. 2000. PMID: 10933942 Free article.

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