Gordon E - Search Results

1

Antiviral properties of aminodiol inhibitors against human immunodeficiency virus and protease.

Bechtold CM, Patick AK, Alam M, Greytok J, Tino JA, Chen P, Gordon E, Ahmad S, Barrish JC, Zahler R, et al. Bechtold CM, et al. Among authors: gordon e. Antimicrob Agents Chemother. 1995 Feb;39(2):374-9. doi: 10.1128/AAC.39.2.374. Antimicrob Agents Chemother. 1995. PMID: 7726501 Free PMC article.

2

Aminodiol HIV protease inhibitors. 1. Design, synthesis, and preliminary SAR.

Barrish JC, Gordon E, Alam M, Lin PF, Bisacchi GS, Chen P, Cheng PT, Fritz AW, Greytok JA, Hermsmeier MA. Barrish JC, et al. Among authors: gordon e. J Med Chem. 1994 Jun 10;37(12):1758-68. doi: 10.1021/jm00038a005. J Med Chem. 1994. PMID: 8021916

3

Phosphinyl acid-based bisubstrate analog inhibitors of Ras farnesyl protein transferase.

Patel DV, Gordon EM, Schmidt RJ, Weller HN, Young MG, Zahler R, Barbacid M, Carboni JM, Gullo-Brown JL, Hunihan L, et al. Patel DV, et al. Among authors: gordon em. J Med Chem. 1995 Feb 3;38(3):435-42. doi: 10.1021/jm00003a006. J Med Chem. 1995. PMID: 7853336

4

Isoprenyl phosphinylformates: new inhibitors of squalene synthetase.

Biller SA, Forster C, Gordon EM, Harrity T, Rich LC, Marretta J, Ciosek CP Jr. Biller SA, et al. Among authors: gordon em. J Med Chem. 1991 Jun;34(6):1912-4. doi: 10.1021/jm00110a024. J Med Chem. 1991. PMID: 2061928 No abstract available.

5

Farnesyl diphosphate-based inhibitors of Ras farnesyl protein transferase.

Patel DV, Schmidt RJ, Biller SA, Gordon EM, Robinson SS, Manne V. Patel DV, et al. Among authors: gordon em. J Med Chem. 1995 Jul 21;38(15):2906-21. doi: 10.1021/jm00015a013. J Med Chem. 1995. PMID: 7636851

6

Hydroxamic acid-based bisubstrate analog inhibitors of Ras farnesyl protein transferase.

Patel DV, Young MG, Robinson SP, Hunihan L, Dean BJ, Gordon EM. Patel DV, et al. Among authors: gordon em. J Med Chem. 1996 Oct 11;39(21):4197-210. doi: 10.1021/jm960190h. J Med Chem. 1996. PMID: 8863797

7

Lipophilic 1,1-bisphosphonates are potent squalene synthase inhibitors and orally active cholesterol lowering agents in vivo.

Ciosek CP Jr, Magnin DR, Harrity TW, Logan JV, Dickson JK Jr, Gordon EM, Hamilton KA, Jolibois KG, Kunselman LK, Lawrence RM, et al. Ciosek CP Jr, et al. Among authors: gordon em. J Biol Chem. 1993 Nov 25;268(33):24832-7. J Biol Chem. 1993. PMID: 8227045 Free article.

8

Phosphorus-containing inhibitors of HMG-CoA reductase. 1. 4-[(2-arylethyl)hydroxyphosphinyl]-3-hydroxy-butanoic acids: a new class of cell-selective inhibitors of cholesterol biosynthesis.

Karanewsky DS, Badia MC, Ciosek CP Jr, Robl JA, Sofia MJ, Simpkins LM, DeLange B, Harrity TW, Biller SA, Gordon EM. Karanewsky DS, et al. Among authors: gordon em. J Med Chem. 1990 Nov;33(11):2952-6. doi: 10.1021/jm00173a007. J Med Chem. 1990. PMID: 2231594 No abstract available.

9

Phosphorus-containing inhibitors of HMG-CoA reductase. 2. Synthesis and biological activities of a series of substituted pyridines containing a hydroxyphosphinyl moiety.

Robl JA, Duncan LA, Pluscec J, Karanewsky DS, Gordon EM, Ciosek CP Jr, Rich LC, Dehmel VC, Slusarchyk DA, Harrity TW, et al. Robl JA, et al. Among authors: gordon em. J Med Chem. 1991 Sep;34(9):2804-15. doi: 10.1021/jm00113a019. J Med Chem. 1991. PMID: 1895299

10

Isoprenoid (phosphinylmethyl)phosphonates as inhibitors of squalene synthetase.

Biller SA, Forster C, Gordon EM, Harrity T, Scott WA, Ciosek CP Jr. Biller SA, et al. Among authors: gordon em. J Med Chem. 1988 Oct;31(10):1869-71. doi: 10.1021/jm00118a001. J Med Chem. 1988. PMID: 3172121 No abstract available.

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