AIDS pathogenesis: HIV envelope and its interaction with cell proteins.
Habeshaw JA, Dalgleish AG, Bountiff L, Newell AL, Wilks D, Walker LC, Manca F.
Habeshaw JA, et al. Among authors: manca f.
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PMID: 2078296
Review.
Abolition of CD4 binding, by denaturation of gp120, allows study of T-cell epitopes in gp120 and shows the denatured molecule is highly immunogenic even in naive subjects (F. Manca, unpublished). The gp120-binding site of CD4 is shared with MHC class II molecules an …
Abolition of CD4 binding, by denaturation of gp120, allows study of T-cell epitopes in gp120 and shows the denatured molecule is highly immu …