Groutas WC - Search Results

1

The Gabriel-Colman rearrangement in biological systems: design, synthesis and biological evaluation of phthalimide and saccharin derivatives as potential mechanism-based inhibitors of human leukocyte elastase, cathepsin G and proteinase 3.

Groutas WC, Chong LS, Venkataraman R, Epp JB, Kuang R, Houser-Archield N, Hoidal JR. Groutas WC, et al. Bioorg Med Chem. 1995 Feb;3(2):187-93. doi: 10.1016/0968-0896(95)00013-7. Bioorg Med Chem. 1995. PMID: 7796053

2

Human neutrophil proteinase 3: mapping of the substrate binding site using peptidyl thiobenzyl esters.

Brubaker MJ, Groutas WC, Hoidal JR, Rao NV. Brubaker MJ, et al. Among authors: groutas wc. Biochem Biophys Res Commun. 1992 Nov 16;188(3):1318-24. doi: 10.1016/0006-291x(92)91375-z. Biochem Biophys Res Commun. 1992. PMID: 1445363

3

Inhibitors of human neutrophil cathepsin G: structural and biochemical studies.

Groutas WC, Brubaker MJ, Venkataraman R, Epp JB, Stanga MA, McClenahan JJ. Groutas WC, et al. Arch Biochem Biophys. 1992 Apr;294(1):144-6. doi: 10.1016/0003-9861(92)90148-p. Arch Biochem Biophys. 1992. PMID: 1497704

4

Enantioselective inhibition of human leukocyte elastase.

Groutas WC, Brubaker MJ, Venkataraman R, Stanga MA. Groutas WC, et al. Arch Biochem Biophys. 1992 Aug 15;297(1):144-6. doi: 10.1016/0003-9861(92)90652-d. Arch Biochem Biophys. 1992. PMID: 1637176

5

Inhibition of human leukocyte elastase by phosphate esters of N-hydroxysuccinimide and its derivatives: direct observation of a phosphorylated enzyme by 31P nuclear magnetic resonance spectroscopy.

Groutas WC, Venkataraman R, Brubaker MJ, Stanga MA. Groutas WC, et al. Biochemistry. 1991 Apr 30;30(17):4132-6. doi: 10.1021/bi00231a004. Biochemistry. 1991. PMID: 2021604

6

Hydantoin derivatives. A new class of inhibitors of human leukocyte elastase.

Groutas WC, Stanga MA, Castrisos JC, Schatz EJ. Groutas WC, et al. J Enzyme Inhib. 1990;3(3):237-43. doi: 10.3109/14756369009035842. J Enzyme Inhib. 1990. PMID: 2079641

7

Ionic inhibitors of human leukocyte elastase: pyridinium and phenyl carboxylate derivatives of 3-alkyl-N-hydroxysuccinimide.

Groutas WC, Stanga MA, Castrisos JC, Schatz EJ, Brubaker MJ. Groutas WC, et al. J Pharm Sci. 1990 Oct;79(10):886-8. doi: 10.1002/jps.2600791008. J Pharm Sci. 1990. PMID: 2280356

8

Inhibitors of human leukocyte proteinase-3.

Groutas WC, Hoidal JR, Brubaker MJ, Stanga MA, Venkataraman R, Gray BH, Rao NV. Groutas WC, et al. J Med Chem. 1990 Apr;33(4):1085-7. doi: 10.1021/jm00166a001. J Med Chem. 1990. PMID: 2319555 No abstract available.

9

Inhibition of human leukocyte elastase by derivatives of N-hydroxysuccinimide. A structure-activity-relationship study.

Groutas WC, Brubaker MJ, Stanga MA, Castrisos JC, Crowley JP, Schatz EJ. Groutas WC, et al. J Med Chem. 1989 Jul;32(7):1607-11. doi: 10.1021/jm00127a034. J Med Chem. 1989. PMID: 2738894

10

Inactivation of leukocyte elastase by aryl azolides and sulfonate salts. Structure-activity relationship studies.

Groutas WC, Brubaker MJ, Zandler ME, Mazo-Gray V, Rude SA, Crowley JP, Castrisos JC, Dunshee DA, Giri PK. Groutas WC, et al. J Med Chem. 1986 Jul;29(7):1302-5. doi: 10.1021/jm00157a034. J Med Chem. 1986. PMID: 3643283

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