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Vaccines prepared with sialyl-Tn and sialyl-Tn trimers using the 4-(4-maleimidomethyl)cyclohexane-1-carboxyl hydrazide linker group result in optimal antibody titers against ovine submaxillary mucin and sialyl-Tn-positive tumor cells.
Ragupathi G, Howard L, Cappello S, Koganty RR, Qiu D, Longenecker BM, Reddish MA, Lloyd KO, Livingston PO. Ragupathi G, et al. Among authors: longenecker bm. Cancer Immunol Immunother. 1999 Apr;48(1):1-8. doi: 10.1007/s002620050542. Cancer Immunol Immunother. 1999. PMID: 10235483 Free PMC article.
Antibodies against mucin-associated sialyl-Tn epitopes correlate with survival of metastatic adenocarcinoma patients undergoing active specific immunotherapy with synthetic STn vaccine.
MacLean GD, Reddish MA, Koganty RR, Longenecker BM. MacLean GD, et al. Among authors: longenecker bm. J Immunother Emphasis Tumor Immunol. 1996 Jan;19(1):59-68. doi: 10.1097/00002371-199601000-00007. J Immunother Emphasis Tumor Immunol. 1996. PMID: 8859725 Clinical Trial.
Immunogenicity and antitumor activity of a liposomal MUC1 peptide-based vaccine.
Samuel J, Budzynski WA, Reddish MA, Ding L, Zimmermann GL, Krantz MJ, Koganty RR, Longenecker BM. Samuel J, et al. Among authors: longenecker bm. Int J Cancer. 1998 Jan 19;75(2):295-302. doi: 10.1002/(sici)1097-0215(19980119)75:2<295::aid-ijc20>3.0.co;2-b. Int J Cancer. 1998. PMID: 9462722
124 results