Robson L - Search Results

1

Purification of bacterially expressed single chain Fv antibodies for clinical applications using metal chelate chromatography.

Casey JL, Keep PA, Chester KA, Robson L, Hawkins RE, Begent RH. Casey JL, et al. Among authors: robson l. J Immunol Methods. 1995 Feb 13;179(1):105-16. doi: 10.1016/0022-1759(94)00278-5. J Immunol Methods. 1995. PMID: 7868918

2

A single chain Fv derived from a filamentous phage library has distinct tumor targeting advantages over one derived from a hybridoma.

Verhaar MJ, Chester KA, Keep PA, Robson L, Pedley RB, Boden JA, Hawkins RE, Begent RH. Verhaar MJ, et al. Among authors: robson l. Int J Cancer. 1995 May 16;61(4):497-501. doi: 10.1002/ijc.2910610412. Int J Cancer. 1995. PMID: 7759155

3

Production and tumour-binding characterization of a chimeric anti-CEA Fab expressed in Escherichia coli.

Chester KA, Robson L, Keep PA, Pedley RB, Boden JA, Boxer GM, Hawkins RE, Begent RH. Chester KA, et al. Among authors: robson l. Int J Cancer. 1994 Apr 1;57(1):67-72. doi: 10.1002/ijc.2910570113. Int J Cancer. 1994. PMID: 8150543

4

Clinical evidence of efficient tumor targeting based on single-chain Fv antibody selected from a combinatorial library.

Begent RH, Verhaar MJ, Chester KA, Casey JL, Green AJ, Napier MP, Hope-Stone LD, Cushen N, Keep PA, Johnson CJ, Hawkins RE, Hilson AJ, Robson L. Begent RH, et al. Among authors: robson l. Nat Med. 1996 Sep;2(9):979-84. doi: 10.1038/nm0996-979. Nat Med. 1996. PMID: 8782454 Clinical Trial.

5

Technetium-99m radiolabeling using a phage-derived single-chain Fv with a C-terminal cysteine.

Verhaar MJ, Keep PA, Hawkins RE, Robson L, Casey JL, Pedley B, Boden JA, Begent RH, Chester KA. Verhaar MJ, et al. Among authors: robson l. J Nucl Med. 1996 May;37(5):868-72. J Nucl Med. 1996. PMID: 8965166 Free article.

6

Clinical applications of phage-derived sFvs and sFv fusion proteins.

Chester KA, Bhatia J, Boxer G, Cooke SP, Flynn AA, Huhalov A, Mayer A, Pedley RB, Robson L, Sharma SK, Spencer DI, Begent RH. Chester KA, et al. Among authors: robson l. Dis Markers. 2000;16(1-2):53-62. doi: 10.1155/2000/672706. Dis Markers. 2000. PMID: 11360829 Free PMC article. Review.

7

A strategy for mapping and neutralizing conformational immunogenic sites on protein therapeutics.

Spencer DI, Robson L, Purdy D, Whitelegg NR, Michael NP, Bhatia J, Sharma SK, Rees AR, Minton NP, Begent RH, Chester KA. Spencer DI, et al. Among authors: robson l. Proteomics. 2002 Mar;2(3):271-9. doi: 10.1002/1615-9861(200203)2:3<271::aid-prot271>3.0.co;2-w. Proteomics. 2002. PMID: 11921443

8

Phage libraries for generation of clinically useful antibodies.

Chester KA, Begent RH, Robson L, Keep P, Pedley RB, Boden JA, Boxer G, Green A, Winter G, Cochet O, et al. Chester KA, et al. Among authors: robson l. Lancet. 1994 Feb 19;343(8895):455-6. doi: 10.1016/s0140-6736(94)92695-6. Lancet. 1994. PMID: 7905958

9

In vitro and in vivo characterisation of a recombinant carboxypeptidase G2::anti-CEA scFv fusion protein.

Michael NP, Chester KA, Melton RG, Robson L, Nicholas W, Boden JA, Pedley RB, Begent RH, Sherwood RF, Minton NP. Michael NP, et al. Among authors: robson l. Immunotechnology. 1996 Feb;2(1):47-57. doi: 10.1016/1380-2933(96)00033-4. Immunotechnology. 1996. PMID: 9373327

10

Recombinant anti-carcinoembryonic antigen antibodies for targeting cancer.

Chester KA, Mayer A, Bhatia J, Robson L, Spencer DI, Cooke SP, Flynn AA, Sharma SK, Boxer G, Pedley RB, Begent RH. Chester KA, et al. Among authors: robson l. Cancer Chemother Pharmacol. 2000;46 Suppl:S8-12. doi: 10.1007/pl00014055. Cancer Chemother Pharmacol. 2000. PMID: 10950140 Review.

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