Chaplin T - Search Results

1

A novel class of zinc finger/leucine zipper genes identified from the molecular cloning of the t(10;11) translocation in acute leukemia.

Chaplin T, Ayton P, Bernard OA, Saha V, Della Valle V, Hillion J, Gregorini A, Lillington D, Berger R, Young BD. Chaplin T, et al. Blood. 1995 Mar 15;85(6):1435-41. Blood. 1995. PMID: 7888665 Free article.

2

The leukemia-associated-protein (LAP) domain, a cysteine-rich motif, is present in a wide range of proteins, including MLL, AF10, and MLLT6 proteins.

Saha V, Chaplin T, Gregorini A, Ayton P, Young BD. Saha V, et al. Among authors: chaplin t. Proc Natl Acad Sci U S A. 1995 Oct 10;92(21):9737-41. doi: 10.1073/pnas.92.21.9737. Proc Natl Acad Sci U S A. 1995. PMID: 7568208 Free PMC article.

3

The t(10;11) translocation in acute myeloid leukemia (M5) consistently fuses the leucine zipper motif of AF10 onto the HRX gene.

Chaplin T, Bernard O, Beverloo HB, Saha V, Hagemeijer A, Berger R, Young BD. Chaplin T, et al. Blood. 1995 Sep 15;86(6):2073-6. Blood. 1995. PMID: 7662954 Free article.

4

The cloning, mapping and expression of a novel gene, BRL, related to the AF10 leukaemia gene.

McCullagh P, Chaplin T, Meerabux J, Grenzelias D, Lillington D, Poulsom R, Gregorini A, Saha V, Young BD. McCullagh P, et al. Among authors: chaplin t. Oncogene. 1999 Dec 9;18(52):7442-52. doi: 10.1038/sj.onc.1203117. Oncogene. 1999. PMID: 10602503

5

The MLL fusion partner AF10 binds GAS41, a protein that interacts with the human SWI/SNF complex.

Debernardi S, Bassini A, Jones LK, Chaplin T, Linder B, de Bruijn DR, Meese E, Young BD. Debernardi S, et al. Among authors: chaplin t. Blood. 2002 Jan 1;99(1):275-81. doi: 10.1182/blood.v99.1.275. Blood. 2002. PMID: 11756182 Free article.

6

Genome-wide analysis of acute myeloid leukemia with normal karyotype reveals a unique pattern of homeobox gene expression distinct from those with translocation-mediated fusion events.

Debernardi S, Lillington DM, Chaplin T, Tomlinson S, Amess J, Rohatiner A, Lister TA, Young BD. Debernardi S, et al. Among authors: chaplin t. Genes Chromosomes Cancer. 2003 Jun;37(2):149-58. doi: 10.1002/gcc.10198. Genes Chromosomes Cancer. 2003. PMID: 12696063

7

Genome-wide single nucleotide polymorphism analysis reveals frequent partial uniparental disomy due to somatic recombination in acute myeloid leukemias.

Raghavan M, Lillington DM, Skoulakis S, Debernardi S, Chaplin T, Foot NJ, Lister TA, Young BD. Raghavan M, et al. Among authors: chaplin t. Cancer Res. 2005 Jan 15;65(2):375-8. Cancer Res. 2005. PMID: 15695375

8

Segmental uniparental disomy is a commonly acquired genetic event in relapsed acute myeloid leukemia.

Raghavan M, Smith LL, Lillington DM, Chaplin T, Kakkas I, Molloy G, Chelala C, Cazier JB, Cavenagh JD, Fitzgibbon J, Lister TA, Young BD. Raghavan M, et al. Among authors: chaplin t. Blood. 2008 Aug 1;112(3):814-21. doi: 10.1182/blood-2008-01-132431. Epub 2008 May 19. Blood. 2008. PMID: 18490517 Free article.

9

The most frequent constitutional translocation in humans, the t(11;22)(q23;q11) is due to a highly specific alu-mediated recombination.

Hill AS, Foot NJ, Chaplin TL, Young BD. Hill AS, et al. Among authors: chaplin tl. Hum Mol Genet. 2000 Jun 12;9(10):1525-32. doi: 10.1093/hmg/9.10.1525. Hum Mol Genet. 2000. PMID: 10888603

10

Molecular cloning and analysis of chromosome band 11q23 involved in leukaemia-associated translocations.

Das S, Kearney L, Bower M, Chaplin T, Riley JH, Anand R, Young BD. Das S, et al. Among authors: chaplin t. Genes Chromosomes Cancer. 1992 Oct;5(3):244-51. doi: 10.1002/gcc.2870050312. Genes Chromosomes Cancer. 1992. PMID: 1384678

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