Lee KH - Search Results

1

Antitumor agents. 155. Synthesis and biological evaluation of 3',6,7-substituted 2-phenyl-4-quinolones as antimicrotubule agents.

Li L, Wang HK, Kuo SC, Wu TS, Mauger A, Lin CM, Hamel E, Lee KH. Li L, et al. Among authors: lee kh. J Med Chem. 1994 Sep 30;37(20):3400-7. doi: 10.1021/jm00046a025. J Med Chem. 1994. PMID: 7932568

2

Antitumor agents. 134. New shiraiachrome-A- and calphostin-C-related perylene derivatives as cytotoxic and antiviral agents and inhibitors of protein kinase C.

Wang HK, Xie JX, Chang JJ, Hwang KM, Liu SY, Ballas LM, Jiang JB, Lee KH. Wang HK, et al. Among authors: lee kh. J Med Chem. 1992 Jul 24;35(15):2717-21. doi: 10.1021/jm00093a001. J Med Chem. 1992. PMID: 1379638

3

Antitumor agents. 111. New 4-hydroxylated and 4-halogenated anilino derivatives of 4'-demethylepipodophyllotoxin as potent inhibitors of human DNA topoisomerase II.

Lee KH, Beers SA, Mori M, Wang ZQ, Kuo YH, Li L, Liu SY, Chang JY, Han FS, Cheng YC. Lee KH, et al. J Med Chem. 1990 May;33(5):1364-8. doi: 10.1021/jm00167a013. J Med Chem. 1990. PMID: 2158562

4

Synthesis of novel water-soluble 7-(aminoacylhydrazono)-formyl camptothecins with potent inhibition of DNA topoisomerase I.

Wang HK, Liu SY, Hwang KM, Taylor G, Lee KH. Wang HK, et al. Among authors: lee kh. Bioorg Med Chem. 1994 Dec;2(12):1397-402. doi: 10.1016/s0968-0896(00)82091-x. Bioorg Med Chem. 1994. PMID: 7788302

5

Antitumor agents. 150. 2',3',4',5',5,6,7-substituted 2-phenyl-4-quinolones and related compounds: their synthesis, cytotoxicity, and inhibition of tubulin polymerization.

Li L, Wang HK, Kuo SC, Wu TS, Lednicer D, Lin CM, Hamel E, Lee KH. Li L, et al. Among authors: lee kh. J Med Chem. 1994 Apr 15;37(8):1126-35. doi: 10.1021/jm00034a010. J Med Chem. 1994. PMID: 8164254

6

Antitumor agents. 141. Synthesis and biological evaluation of novel thiocolchicine analogs: N-acyl-, N-aroyl-, and N-(substituted benzyl)deacetylthiocolchicines as potent cytotoxic and antimitotic compounds.

Sun L, Hamel E, Lin CM, Hastie SB, Pyluck A, Lee KH. Sun L, et al. Among authors: lee kh. J Med Chem. 1993 May 14;36(10):1474-9. doi: 10.1021/jm00062a021. J Med Chem. 1993. PMID: 8496915

7

Antitumor agents. 139. Synthesis and biological evaluation of thiocolchicine analogs 5,6-dihydro-6(S)-(acyloxy)- and 5,6-dihydro-6(S)-[(aroyloxy)methyl]-1,2,3-trimethoxy-9-(methylthio)-8H- cyclohepta[a]naphthalen-8-ones as novel cytotoxic and antimitotic agents.

Sun L, McPhail AT, Hamel E, Lin CM, Hastie SB, Chang JJ, Lee KH. Sun L, et al. Among authors: lee kh. J Med Chem. 1993 Mar 5;36(5):544-51. doi: 10.1021/jm00057a004. J Med Chem. 1993. PMID: 8496935

8

Antitumor agents. 166. Synthesis and biological evaluation of 5,6,7,8-substituted-2-phenylthiochromen-4-ones.

Wang HK, Bastow KF, Cosentino LM, Lee KH. Wang HK, et al. Among authors: lee kh. J Med Chem. 1996 May 10;39(10):1975-80. doi: 10.1021/jm960008c. J Med Chem. 1996. PMID: 8642556

9

Antitumor agents. 172. Synthesis and biological evaluation of novel deacetamidothiocolchicin-7-ols and ester analogs as antitubulin agents.

Shi Q, Verdier-Pinard P, Brossi A, Hamel E, McPhail AT, Lee KH. Shi Q, et al. Among authors: lee kh. J Med Chem. 1997 Mar 14;40(6):961-6. doi: 10.1021/jm960663k. J Med Chem. 1997. PMID: 9083485

10

Recent advances in the discovery and development of topoisomerase inhibitors as antitumor agents.

Wang HK, Morris-Natschke SL, Lee KH. Wang HK, et al. Among authors: lee kh. Med Res Rev. 1997 Jul;17(4):367-425. doi: 10.1002/(sici)1098-1128(199707)17:4<367::aid-med3>3.0.co;2-u. Med Res Rev. 1997. PMID: 9211397 Review. No abstract available.

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