Darbyshire JF - Search Results

1

Reaction kinetics for nitrosation of cysteine and glutathione in aerobic nitric oxide solutions at neutral pH. Insights into the fate and physiological effects of intermediates generated in the NO/O2 reaction.

Wink DA, Nims RW, Darbyshire JF, Christodoulou D, Hanbauer I, Cox GW, Laval F, Laval J, Cook JA, Krishna MC, et al. Wink DA, et al. Among authors: darbyshire jf. Chem Res Toxicol. 1994 Jul-Aug;7(4):519-25. doi: 10.1021/tx00040a007. Chem Res Toxicol. 1994. PMID: 7981416

2

Reactions of the bioregulatory agent nitric oxide in oxygenated aqueous media: determination of the kinetics for oxidation and nitrosation by intermediates generated in the NO/O2 reaction.

Wink DA, Darbyshire JF, Nims RW, Saavedra JE, Ford PC. Wink DA, et al. Among authors: darbyshire jf. Chem Res Toxicol. 1993 Jan-Feb;6(1):23-7. doi: 10.1021/tx00031a003. Chem Res Toxicol. 1993. PMID: 8448345 Free article.

3

Inhibition of cytochromes P450 by nitric oxide and a nitric oxide-releasing agent.

Wink DA, Osawa Y, Darbyshire JF, Jones CR, Eshenaur SC, Nims RW. Wink DA, et al. Among authors: darbyshire jf. Arch Biochem Biophys. 1993 Jan;300(1):115-23. doi: 10.1006/abbi.1993.1016. Arch Biochem Biophys. 1993. PMID: 8424643

4

pH-dependent one- and two-electron oxidation of 3,5-dicarbethoxy-2,6-dimethyl-4-ethyl-1,4-dihydropyridine catalyzed by horseradish peroxidase.

Sugiyama K, Correia MA, Thummel KE, Nagata K, Darbyshire JF, Osawa Y, Gillette JR. Sugiyama K, et al. Among authors: darbyshire jf. Chem Res Toxicol. 1994 Sep-Oct;7(5):633-42. doi: 10.1021/tx00041a008. Chem Res Toxicol. 1994. PMID: 7841342

5

Inactivation of horseradish peroxidase by 3,5-dicarbethoxy-2,6-dimethyl-4-ethyl-1,4-dihydropyridine.

Sugiyama K, Woods A, Cotter RJ, Highet RJ, Darbyshire JF, Osawa Y, Gillette JR. Sugiyama K, et al. Among authors: darbyshire jf. Chem Res Toxicol. 1994 Nov-Dec;7(6):843-9. doi: 10.1021/tx00042a019. Chem Res Toxicol. 1994. PMID: 7696541

6

Control of activity through oxidative modification at the conserved residue Cys66 of aryl sulfotransferase IV.

Marshall AD, Darbyshire JF, Hunter AP, McPhie P, Jakoby WB. Marshall AD, et al. Among authors: darbyshire jf. J Biol Chem. 1997 Apr 4;272(14):9153-60. doi: 10.1074/jbc.272.14.9153. J Biol Chem. 1997. PMID: 9139043 Free article.

7

Inhibition of P450 cytochromes by reactive intermediates.

Osawa Y, Davila JC, Nakatsuka M, Meyer CA, Darbyshire JF. Osawa Y, et al. Among authors: darbyshire jf. Drug Metab Rev. 1995;27(1-2):61-72. doi: 10.3109/03602539509029815. Drug Metab Rev. 1995. PMID: 7641585 Review. No abstract available.

8

Intramolecular isotope effects for benzylic hydroxylation of isomeric xylenes and 4,4'-dimethylbiphenyl by cytochrome P450: relationship between distance of methyl groups and masking of the intrinsic isotope effect.

Iyer KR, Jones JP, Darbyshire JF, Trager WF. Iyer KR, et al. Among authors: darbyshire jf. Biochemistry. 1997 Jun 10;36(23):7136-43. doi: 10.1021/bi962810m. Biochemistry. 1997. PMID: 9188713

9

12 alpha-hydroxytestosterone. A hitherto unidentified testosterone metabolite produced by cytochrome P-450 2A2.

Smith SJ, Korzekwa KR, Aoyama T, Gonzalez FJ, Darbyshire JF, Sugiyama K, Gillette JR. Smith SJ, et al. Among authors: darbyshire jf. Drug Metab Dispos. 1992 Jul-Aug;20(4):566-71. Drug Metab Dispos. 1992. PMID: 1356736

10

Theoretical kinetics of sequential metabolism in vitro. Study of the formation of 16 alpha-hydroxyandrostenedione from testosterone by purified rat P450 2C11.

Sugiyama K, Nagata K, Gillette JR, Darbyshire JF. Sugiyama K, et al. Among authors: darbyshire jf. Drug Metab Dispos. 1994 Jul-Aug;22(4):584-91. Drug Metab Dispos. 1994. PMID: 7956734

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