A possible initial folding intermediate: the C-terminal proteolytic domain of tryptophan synthase beta chains folds in less than 4 milliseconds into a condensed state with non-native-like secondary structure.
Chaffotte AF, Cadieux C, Guillou Y, Goldberg ME.
Chaffotte AF, et al.
Biochemistry. 1992 May 5;31(17):4303-8. doi: 10.1021/bi00132a022.
Biochemistry. 1992.
PMID: 1567876
However, this state has non-native-like secondary and supersecondary structures [Chaffotte, A., Guillou, Y., Delepierre, M., Hinz, H.-J., & Goldberg, M. E. (1991) Biochemistry 30, 8067-8074]. ...These observations strongly suggest that the previously described c …
However, this state has non-native-like secondary and supersecondary structures [Chaffotte, A., Guillou, Y., Delepierre, M., H …