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L-687,781, a new member of the papulacandin family of beta-1,3-D-glucan synthesis inhibitors. I. Fermentation, isolation, and biological activity.
VanMiddlesworth F, Omstead MN, Schmatz D, Bartizal K, Fromtling R, Bills G, Nollstadt K, Honeycutt S, Zweerink M, Garrity G, et al. VanMiddlesworth F, et al. Among authors: bartizal k. J Antibiot (Tokyo). 1991 Jan;44(1):45-51. doi: 10.7164/antibiotics.44.45. J Antibiot (Tokyo). 1991. PMID: 2001985 Free article.
In vitro antifungal activities and in vivo efficacies of 1,3-beta-D-glucan synthesis inhibitors L-671,329, L-646,991, tetrahydroechinocandin B, and L-687,781, a papulacandin.
Bartizal K, Abruzzo G, Trainor C, Krupa D, Nollstadt K, Schmatz D, Schwartz R, Hammond M, Balkovec J, Vanmiddlesworth F. Bartizal K, et al. Antimicrob Agents Chemother. 1992 Aug;36(8):1648-57. doi: 10.1128/AAC.36.8.1648. Antimicrob Agents Chemother. 1992. PMID: 1416847 Free PMC article.
Synthesis, stability, and biological evaluation of water-soluble prodrugs of a new echinocandin lipopeptide. Discovery of a potential clinical agent for the treatment of systemic candidiasis and Pneumocystis carinii pneumonia (PCP).
Balkovec JM, Black RM, Hammond ML, Heck JV, Zambias RA, Abruzzo G, Bartizal K, Kropp H, Trainor C, Schwartz RE, et al. Balkovec JM, et al. Among authors: bartizal k. J Med Chem. 1992 Jan;35(1):194-8. doi: 10.1021/jm00079a027. J Med Chem. 1992. PMID: 1732529 No abstract available.
The discovery of a potent and selective lethal factor inhibitor for adjunct therapy of anthrax infection.
Xiong Y, Wiltsie J, Woods A, Guo J, Pivnichny JV, Tang W, Bansal A, Cummings RT, Cunningham BR, Friedlander AM, Douglas CM, Salowe SP, Zaller DM, Scolnick EM, Schmatz DM, Bartizal K, Hermes JD, MacCoss M, Chapman KT. Xiong Y, et al. Among authors: bartizal k. Bioorg Med Chem Lett. 2006 Feb 15;16(4):964-8. doi: 10.1016/j.bmcl.2005.10.088. Epub 2005 Dec 9. Bioorg Med Chem Lett. 2006. PMID: 16338135
63 results