Block TM - Search Results

1

Secretion of human hepatitis B virus is inhibited by the imino sugar N-butyldeoxynojirimycin.

Block TM, Lu X, Platt FM, Foster GR, Gerlich WH, Blumberg BS, Dwek RA. Block TM, et al. Proc Natl Acad Sci U S A. 1994 Mar 15;91(6):2235-9. doi: 10.1073/pnas.91.6.2235. Proc Natl Acad Sci U S A. 1994. PMID: 8134380 Free PMC article.

2

Evidence that N-linked glycosylation is necessary for hepatitis B virus secretion.

Lu X, Mehta A, Dwek R, Butters T, Block T. Lu X, et al. Virology. 1995 Nov 10;213(2):660-5. doi: 10.1006/viro.1995.0038. Virology. 1995. PMID: 7491790 Free article.

3

Aberrant trafficking of hepatitis B virus glycoproteins in cells in which N-glycan processing is inhibited.

Lu X, Mehta A, Dadmarz M, Dwek R, Blumberg BS, Block TM. Lu X, et al. Among authors: block tm. Proc Natl Acad Sci U S A. 1997 Mar 18;94(6):2380-5. doi: 10.1073/pnas.94.6.2380. Proc Natl Acad Sci U S A. 1997. PMID: 9122203 Free PMC article.

4

Imino sugars inhibit the formation and secretion of bovine viral diarrhea virus, a pestivirus model of hepatitis C virus: implications for the development of broad spectrum anti-hepatitis virus agents.

Zitzmann N, Mehta AS, Carrouée S, Butters TD, Platt FM, McCauley J, Blumberg BS, Dwek RA, Block TM. Zitzmann N, et al. Among authors: block tm. Proc Natl Acad Sci U S A. 1999 Oct 12;96(21):11878-82. doi: 10.1073/pnas.96.21.11878. Proc Natl Acad Sci U S A. 1999. PMID: 10518544 Free PMC article.

5

Inhibition of hepatitis B virus DNA replication by imino sugars without the inhibition of the DNA polymerase: therapeutic implications.

Mehta A, Carrouée S, Conyers B, Jordan R, Butters T, Dwek RA, Block TM. Mehta A, et al. Among authors: block tm. Hepatology. 2001 Jun;33(6):1488-95. doi: 10.1053/jhep.2001.25103. Hepatology. 2001. PMID: 11391538

6

Hepatitis B virus (HBV) envelope glycoproteins vary drastically in their sensitivity to glycan processing: evidence that alteration of a single N-linked glycosylation site can regulate HBV secretion.

Mehta A, Lu X, Block TM, Blumberg BS, Dwek RA. Mehta A, et al. Among authors: block tm. Proc Natl Acad Sci U S A. 1997 Mar 4;94(5):1822-7. doi: 10.1073/pnas.94.5.1822. Proc Natl Acad Sci U S A. 1997. PMID: 9050863 Free PMC article.

7

Study of the early steps of the Hepatitis B Virus life cycle.

Lu X, Block T. Lu X, et al. Int J Med Sci. 2004;1(1):21-33. doi: 10.7150/ijms.1.21. Epub 2004 Mar 10. Int J Med Sci. 2004. PMID: 15912187 Free PMC article.

8

Hepatitis B virus large and middle glycoproteins are degraded by a proteasome pathway in glucosidase-inhibited cells but not in cells with functional glucosidase enzyme.

Simsek E, Mehta A, Zhou T, Dwek RA, Block T. Simsek E, et al. J Virol. 2005 Oct;79(20):12914-20. doi: 10.1128/JVI.79.20.12914-12920.2005. J Virol. 2005. PMID: 16188993 Free PMC article.

9

The combination of interferon alpha-2b and n-butyl deoxynojirimycin has a greater than additive antiviral effect upon production of infectious bovine viral diarrhea virus (BVDV) in vitro: implications for hepatitis C virus (HCV) therapy.

Ouzounov S, Mehta A, Dwek RA, Block TM, Jordan R. Ouzounov S, et al. Among authors: block tm. Antiviral Res. 2002 Sep;55(3):425-35. doi: 10.1016/s0166-3542(02)00075-x. Antiviral Res. 2002. PMID: 12206880

10

Structure-activity relationship of a new class of anti-hepatitis B virus agents.

Mehta A, Conyers B, Tyrrell DL, Walters KA, Tipples GA, Dwek RA, Block TM. Mehta A, et al. Among authors: block tm. Antimicrob Agents Chemother. 2002 Dec;46(12):4004-8. doi: 10.1128/AAC.46.12.4004-4008.2002. Antimicrob Agents Chemother. 2002. PMID: 12435712 Free PMC article.

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