Corbett TH - Search Results

1

Comparative molecular field analysis of the antitumor activity of 9H-thioxanthen-9-one derivatives against pancreatic ductal carcinoma 03.

Horwitz JP, Massova I, Wiese TE, Besler BH, Corbett TH. Horwitz JP, et al. Among authors: corbett th. J Med Chem. 1994 Mar 18;37(6):781-6. doi: 10.1021/jm00032a010. J Med Chem. 1994. PMID: 8145227

2

Synthetic modification of the 2-oxypropionic acid moiety in 2-{4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy}propionic acid (XK469), and consequent antitumor effects. Part 4.

Hazeldine ST, Polin L, Kushner J, White K, Corbett TH, Horwitz JP. Hazeldine ST, et al. Among authors: corbett th. Bioorg Med Chem. 2005 Jun 2;13(12):3910-20. doi: 10.1016/j.bmc.2005.04.011. Bioorg Med Chem. 2005. PMID: 15911307

3

Comparative molecular field analysis of in vitro growth inhibition of L1210 and HCT-8 cells by some pyrazoloacridines.

Horwitz JP, Massova I, Wiese TE, Wozniak AJ, Corbett TH, Sebolt-Leopold JS, Capps DB, Leopold WR. Horwitz JP, et al. Among authors: corbett th. J Med Chem. 1993 Nov 12;36(23):3511-6. doi: 10.1021/jm00075a004. J Med Chem. 1993. PMID: 8280289

4

Design, synthesis, and biological evaluation of analogues of the antitumor agent, 2-(4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy)propionic acid (XK469).

Hazeldine ST, Polin L, Kushner J, Paluch J, White K, Edelstein M, Palomino E, Corbett TH, Horwitz JP. Hazeldine ST, et al. Among authors: corbett th. J Med Chem. 2001 May 24;44(11):1758-76. doi: 10.1021/jm0005149. J Med Chem. 2001. PMID: 11356111

5

Part 3: synthesis and biological evaluation of some analogs of the antitumor agents, 2-{4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy}propionic acid, and 2-{4-[(7-bromo-2-quinolinyl)oxy]phenoxy}propionic acid.

Hazeldine ST, Polin L, Kushner J, White K, Corbett TH, Biehl J, Horwitz JP. Hazeldine ST, et al. Among authors: corbett th. Bioorg Med Chem. 2005 Feb 15;13(4):1069-81. doi: 10.1016/j.bmc.2004.11.034. Bioorg Med Chem. 2005. PMID: 15670915

6

Synthesis and biological evaluation of conformationally constrained analogs of the antitumor agents XK469 and SH80. Part 5.

Hazeldine ST, Polin L, Kushner J, White K, Corbett TH, Horwitz JP. Hazeldine ST, et al. Among authors: corbett th. Bioorg Med Chem. 2006 Apr 1;14(7):2462-7. doi: 10.1016/j.bmc.2005.11.036. Epub 2005 Dec 5. Bioorg Med Chem. 2006. PMID: 16337128

7

II. Synthesis and biological evaluation of some bioisosteres and congeners of the antitumor agent, 2-(4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy)propionic acid (XK469).

Hazeldine ST, Polin L, Kushner J, White K, Bouregeois NM, Crantz B, Palomino E, Corbett TH, Horwitz JP. Hazeldine ST, et al. Among authors: corbett th. J Med Chem. 2002 Jul 4;45(14):3130-7. doi: 10.1021/jm0200097. J Med Chem. 2002. PMID: 12086498

8

Lack of in vitro-in vivo correlation of a novel investigational anticancer agent, SH 30.

Poondru S, Parchment RE, Purohit V, LoRusso P, Horwitz JP, Hazeldine ST, Polin L, Corbett T, Jasti BR. Poondru S, et al. Invest New Drugs. 2002 Feb;20(1):23-33. doi: 10.1023/a:1014457510073. Invest New Drugs. 2002. PMID: 12003192

9

Identification and antitumor activity of a reduction product in the murine metabolism of pyrazoloacridine (NSC-366140).

Palomino E, Foster B, Kempff M, Corbett T, Wiegand R, Horwitz J, Baker L. Palomino E, et al. Cancer Chemother Pharmacol. 1996;38(5):453-8. doi: 10.1007/s002800050510. Cancer Chemother Pharmacol. 1996. PMID: 8765439

10

Preclinical antitumor efficacy of analogs of XK469: sodium-(2-[4-(7-chloro-2-quinoxalinyloxy)phenoxy]propionate.

Corbett TH, LoRusso P, Demchick L, Simpson C, Pugh S, White K, Kushner J, Polin L, Meyer J, Czarnecki J, Heilbrun L, Horwitz JP, Gross JL, Behrens CH, Harrison BA, McRipley RJ, Trainor G. Corbett TH, et al. Invest New Drugs. 1998;16(2):129-39. doi: 10.1023/a:1006174622061. Invest New Drugs. 1998. PMID: 9848576

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