Wikström H - Search Results

1

Orally active central dopamine and serotonin receptor ligands: 5-, 6-, 7-, and 8-[[trifluoromethyl)sulfonyl]oxy]-2-(di-n-propylamino)tetralins and the formation of active metabolites in vivo.

Sonesson C, Boije M, Svensson K, Ekman A, Carlsson A, Romero AG, Martin IJ, Duncan JN, King LJ, Wikström H. Sonesson C, et al. Among authors: wikstrom h. J Med Chem. 1993 Oct 29;36(22):3409-16. doi: 10.1021/jm00074a022. J Med Chem. 1993. PMID: 8230131

2

6-Hydroxy-3-n-propyl-2,3,4,5-tetrahydro-1H-3-benzazepine and analogs: new centrally acting 5-HT1A receptor agonists.

Wikström H, Andersson B, Elebring T, Lagerkvist S, Hallnemo G, Pettersson I, Jovall PA, Svensson K, Ekman A, Carlsson A. Wikström H, et al. J Med Chem. 1992 Oct 30;35(22):3984-90. doi: 10.1021/jm00100a002. J Med Chem. 1992. PMID: 1433207

3

Pre- and postsynaptic dopaminergic activities of indolizidine and quinolizidine derivatives of 3-(3-hydroxyphenyl)-N-(n-propyl)piperidine (3-PPP). Further developments of a dopamine receptor model.

Liljefors T, Bøgesø KP, Hyttel J, Wikström H, Svensson K, Carlsson A. Liljefors T, et al. Among authors: wikstrom h. J Med Chem. 1990 Mar;33(3):1015-22. doi: 10.1021/jm00165a020. J Med Chem. 1990. PMID: 1968512

4

Resolved 6,7,8,9-tetrahydro-N,N-dimethyl-3H-benz[e]indol-8-amine: central dopamine and serotonin receptor stimulating properties.

Wikström H, Andersson B, Svensson A, Humber LG, Asselin AA, Svensson K, Ekman A, Carlsson A, Nilsson I, Chidester C. Wikström H, et al. J Med Chem. 1989 Oct;32(10):2273-6. doi: 10.1021/jm00130a008. J Med Chem. 1989. PMID: 2571729

5

N-substituted 1,2,3,4,4a,5,6,10b-octahydrobenzo[f]quinolines and 3-phenylpiperidines: effects on central dopamine and sigma receptors.

Wikström H, Andersson B, Elebring T, Svensson K, Carlsson A, Largent B. Wikström H, et al. J Med Chem. 1987 Dec;30(12):2169-74. doi: 10.1021/jm00395a002. J Med Chem. 1987. PMID: 2824773

6

(+)-cis-8-Hydroxy-1-methyl-2-(di-n-propylamino)tetralin: a potent and highly stereoselective 5-hydroxytryptamine receptor agonist.

Arvidsson LE, Johansson AM, Hacksell U, Nilsson JL, Svensson K, Hjorth S, Magnusson T, Carlsson A, Andersson B, Wikström H. Arvidsson LE, et al. Among authors: wikstrom h. J Med Chem. 1987 Nov;30(11):2105-9. doi: 10.1021/jm00394a029. J Med Chem. 1987. PMID: 2959776

7

Occurrence and pharmacological significance of metabolic ortho-hydroxylation of 5- and 8-hydroxy-2-(di-n-propylamino)tetralin.

Wikström H, Elebring T, Hallnemo G, Andersson B, Svensson K, Carlsson A, Rollema H. Wikström H, et al. J Med Chem. 1988 Jun;31(6):1080-4. doi: 10.1021/jm00401a005. J Med Chem. 1988. PMID: 2967374

8

Structure-activity relationships in the 8-amino-6,7,8,9-tetrahydro-3H-benz[e]indole ring system. 1. Effects of substituents in the aromatic system on serotonin and dopamine receptor subtypes.

Stjernlöf P, Ennis MD, Hansson LO, Hoffman RL, Ghazal NB, Sundell S, Smith MW, Svensson K, Carlsson A, Wikström H. Stjernlöf P, et al. Among authors: wikstrom h. J Med Chem. 1995 Jun 9;38(12):2202-16. doi: 10.1021/jm00012a021. J Med Chem. 1995. PMID: 7783152

9

6,7,8,9-Tetrahydro-N,N-di-n-propyl-3H-benzindol-8-amines. Derivatives as potent and orally active serotonin 5-HT1A receptor agonists.

Stjernlöf P, Elebring T, Nilsson J, Andersson B, Lagerkvist S, Svensson K, Ekman A, Carlsson A, Wikström H. Stjernlöf P, et al. Among authors: wikstrom h. J Med Chem. 1994 Sep 30;37(20):3263-73. doi: 10.1021/jm00046a010. J Med Chem. 1994. PMID: 7932553

10

Substituted (S)-phenylpiperidines and rigid congeners as preferential dopamine autoreceptor antagonists: synthesis and structure-activity relationships.

Sonesson C, Lin CH, Hansson L, Waters N, Svensson K, Carlsson A, Smith MW, Wikström H. Sonesson C, et al. Among authors: wikstrom h. J Med Chem. 1994 Aug 19;37(17):2735-53. doi: 10.1021/jm00043a013. J Med Chem. 1994. PMID: 8064801

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