Lin CH - Search Results

1

Centrally acting serotonergic agents. Synthesis and structure-activity relationships of C-1- or C-3-substituted derivatives of 8-hydroxy-2-(di-n-propylamino)tetralin.

Lin CH, Haadsma-Svensson SR, Lahti RA, McCall RB, Piercey MF, Schreur PJ, VonVoigtlander PF, Chidester CG. Lin CH, et al. J Med Chem. 1993 Mar 19;36(6):671-82. doi: 10.1021/jm00058a003. J Med Chem. 1993. PMID: 8459396

2

Structure-activity relationships in the 8-amino-6,7,8,9-tetrahydro-3H-benz[e]indole ring system. 2. Effects of 8-amino nitrogen substitution on serotonin receptor binding and pharmacology.

Ennis MD, Stjernlöf P, Hoffman RL, Ghazal NB, Smith MW, Svensson K, Wikström H, Haadsma-Svensson SR, Lin CH. Ennis MD, et al. Among authors: lin ch. J Med Chem. 1995 Jun 9;38(12):2217-30. doi: 10.1021/jm00012a022. J Med Chem. 1995. PMID: 7783153

3

C-9 and N-substituted analogs of cis-(3aR)-(-)-2,3,3a,4,5,9b-hexahydro-3- propyl-1H-benz[e]indole-9-carboxamide: 5-HT1A receptor agonists with various degrees of metabolic stability.

Haadsma-Svensson SR, Svensson K, Duncan N, Smith MW, Lin CH. Haadsma-Svensson SR, et al. Among authors: lin ch. J Med Chem. 1995 Feb 17;38(4):725-34. doi: 10.1021/jm00004a018. J Med Chem. 1995. PMID: 7861420

4

Centrally acting serotonergic and dopaminergic agents. 1. Synthesis and structure-activity relationships of 2,3,3a,4,5,9b-hexahydro-1H-benz[e]indole derivatives.

Lin CH, Haadsma-Svensson SR, Lahti RA, McCall RB, Piercey MF, Schreur PJ, Von Voigtlander PF, Smith MW, Chidester CG. Lin CH, et al. J Med Chem. 1993 Apr 16;36(8):1053-68. doi: 10.1021/jm00060a014. J Med Chem. 1993. PMID: 8097537

5

Centrally acting serotonergic and dopaminergic agents. 2. Synthesis and structure-activity relationships of 2,3,3a,4,9,9a-hexahydro-1H-benz[f]indole derivatives.

Lin CH, Haadsma-Svensson SR, Phillips G, Lahti RA, McCall RB, Piercey MF, Schreur PJ, Von Voigtlander PF, Smith MW, Chidester CG. Lin CH, et al. J Med Chem. 1993 Apr 16;36(8):1069-83. doi: 10.1021/jm00060a015. J Med Chem. 1993. PMID: 8097538

6

Synthesis and biological activity of cis-(3aR)-(-)-2,3,3a,4,5,9b-hexahydro- 3-propyl-1H-benz[e]indole-9-carboxamide: a potent and selective 5-HT1A receptor agonist with good oral availability.

Lin CH, Haadsma-Svensson SR, Phillips G, McCall RB, Piercey MF, Smith MW, Svensson K, Carlsson A, Chidester CG, Von Voigtlander PF. Lin CH, et al. J Med Chem. 1993 Jul 23;36(15):2208-18. doi: 10.1021/jm00067a018. J Med Chem. 1993. PMID: 8340922

7

Comparison of 5-HT1A and dopamine D2 pharmacophores. X-ray structures and affinities of conformationally constrained ligands.

Chidester CG, Lin CH, Lahti RA, Haadsma-Svensson SR, Smith MW. Chidester CG, et al. Among authors: lin ch. J Med Chem. 1993 May 14;36(10):1301-15. doi: 10.1021/jm00062a001. J Med Chem. 1993. PMID: 8496900

8

Dopamine D(3) receptor antagonists. 1. Synthesis and structure-activity relationships of 5,6-dimethoxy-N-alkyl- and N-alkylaryl-substituted 2-aminoindans.

Haadsma-Svensson SR, Cleek KA, Dinh DM, Duncan JN, Haber CL, Huff RM, Lajiness ME, Nichols NF, Smith MW, Svensson KA, Zaya MJ, Carlsson A, Lin CH. Haadsma-Svensson SR, et al. Among authors: lin ch. J Med Chem. 2001 Dec 20;44(26):4716-32. doi: 10.1021/jm010145w. J Med Chem. 2001. PMID: 11741489

9

Substituted (S)-phenylpiperidines and rigid congeners as preferential dopamine autoreceptor antagonists: synthesis and structure-activity relationships.

Sonesson C, Lin CH, Hansson L, Waters N, Svensson K, Carlsson A, Smith MW, Wikström H. Sonesson C, et al. Among authors: lin ch. J Med Chem. 1994 Aug 19;37(17):2735-53. doi: 10.1021/jm00043a013. J Med Chem. 1994. PMID: 8064801

10

Studies on chemical modification and biology of a natural product, gambogic acid (III): determination of the essential pharmacophore for biological activity.

Wang X, Lu N, Yang Q, Gong D, Lin C, Zhang S, Xi M, Gao Y, Wei L, Guo Q, You Q. Wang X, et al. Eur J Med Chem. 2011 Apr;46(4):1280-90. doi: 10.1016/j.ejmech.2011.01.051. Epub 2011 Feb 3. Eur J Med Chem. 2011. PMID: 21334116

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