Brickner SJ - Search Results

1

Synthesis and antibacterial activity of U-100592 and U-100766, two oxazolidinone antibacterial agents for the potential treatment of multidrug-resistant gram-positive bacterial infections.

Brickner SJ, Hutchinson DK, Barbachyn MR, Manninen PR, Ulanowicz DA, Garmon SA, Grega KC, Hendges SK, Toops DS, Ford CW, Zurenko GE. Brickner SJ, et al. J Med Chem. 1996 Feb 2;39(3):673-9. doi: 10.1021/jm9509556. J Med Chem. 1996. PMID: 8576909

2

Linezolid (ZYVOX), the first member of a completely new class of antibacterial agents for treatment of serious gram-positive infections.

Brickner SJ, Barbachyn MR, Hutchinson DK, Manninen PR. Brickner SJ, et al. J Med Chem. 2008 Apr 10;51(7):1981-90. doi: 10.1021/jm800038g. Epub 2008 Mar 14. J Med Chem. 2008. PMID: 18338841 Review. No abstract available.

3

N-acyl 3-alkylidenyl- and 3-alkyl azetidin-2-ones: a new class of monocyclic beta-lactam antibacterial agents. 1. Structure-activity relationships of 3-isopropylidene and 3-isopropyl analogs.

Brickner SJ, Gaikema JJ, Zurenko GE, Greenfield LJ, Manninen PR, Ulanowicz DA. Brickner SJ, et al. J Antibiot (Tokyo). 1992 Feb;45(2):213-26. doi: 10.7164/antibiotics.45.213. J Antibiot (Tokyo). 1992. PMID: 1556013 Free article.

4

Identification of a novel oxazolidinone (U-100480) with potent antimycobacterial activity.

Barbachyn MR, Hutchinson DK, Brickner SJ, Cynamon MH, Kilburn JO, Klemens SP, Glickman SE, Grega KC, Hendges SK, Toops DS, Ford CW, Zurenko GE. Barbachyn MR, et al. Among authors: brickner sj. J Med Chem. 1996 Feb 2;39(3):680-5. doi: 10.1021/jm950956y. J Med Chem. 1996. PMID: 8576910

5

In vivo activities of U-100592 and U-100766, novel oxazolidinone antimicrobial agents, against experimental bacterial infections.

Ford CW, Hamel JC, Wilson DM, Moerman JK, Stapert D, Yancey RJ Jr, Hutchinson DK, Barbachyn MR, Brickner SJ. Ford CW, et al. Among authors: brickner sj. Antimicrob Agents Chemother. 1996 Jun;40(6):1508-13. doi: 10.1128/AAC.40.6.1508. Antimicrob Agents Chemother. 1996. PMID: 8726028 Free PMC article.

6

In vitro activities of U-100592 and U-100766, novel oxazolidinone antibacterial agents.

Zurenko GE, Yagi BH, Schaadt RD, Allison JW, Kilburn JO, Glickman SE, Hutchinson DK, Barbachyn MR, Brickner SJ. Zurenko GE, et al. Among authors: brickner sj. Antimicrob Agents Chemother. 1996 Apr;40(4):839-45. doi: 10.1128/AAC.40.4.839. Antimicrob Agents Chemother. 1996. PMID: 8849237 Free PMC article.

7

Piperazinyl oxazolidinone antibacterial agents containing a pyridine, diazene, or triazene heteroaromatic ring.

Tucker JA, Allwine DA, Grega KC, Barbachyn MR, Klock JL, Adamski JL, Brickner SJ, Hutchinson DK, Ford CW, Zurenko GE, Conradi RA, Burton PS, Jensen RM. Tucker JA, et al. Among authors: brickner sj. J Med Chem. 1998 Sep 10;41(19):3727-35. doi: 10.1021/jm980274l. J Med Chem. 1998. PMID: 9733498

8

Synthesis and antibacterial activity of [6,5,5] and [6,6,5] tricyclic fused oxazolidinones.

Gleave DM, Brickner SJ, Manninen PR, Allwine DA, Lovasz KD, Rohrer DC, Tucker JA, Zurenko GE, Ford CW. Gleave DM, et al. Among authors: brickner sj. Bioorg Med Chem Lett. 1998 May 19;8(10):1231-6. doi: 10.1016/s0960-894x(98)00194-2. Bioorg Med Chem Lett. 1998. PMID: 9871741

9

Design, synthesis, and evaluation of novel oxazolidinone antibacterial agents active against multidrug-resistant bacteria.

Barbachyn MR, Brickner SJ, Gadwood RC, Garmon SA, Grega KC, Hutchinson DK, Munesada K, Reischer RJ, Taniguchi M, Thomasco LM, Toops DS, Yamada H, Ford CW, Zurenko GE. Barbachyn MR, et al. Among authors: brickner sj. Adv Exp Med Biol. 1998;456:219-38. doi: 10.1007/978-1-4615-4897-3_12. Adv Exp Med Biol. 1998. PMID: 10549371 Review. No abstract available.

10

Oxazolidinone antibacterial agents: development of the clinical candidates eperezolid and linezolid.

Zurenko GE, Ford CW, Hutchinson DK, Brickner SJ, Barbachyn MR. Zurenko GE, et al. Among authors: brickner sj. Expert Opin Investig Drugs. 1997 Feb;6(2):151-8. doi: 10.1517/13543784.6.2.151. Expert Opin Investig Drugs. 1997. PMID: 15989598

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