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Mechanism of anti-human immunodeficiency virus activity of beta-D-6-cyclopropylamino-2',3'-didehydro-2',3'-dideoxyguanosine.
Ray AS, Hernandez-Santiago BI, Mathew JS, Murakami E, Bozeman C, Xie MY, Dutschman GE, Gullen E, Yang Z, Hurwitz S, Cheng YC, Chu CK, McClure H, Schinazi RF, Anderson KS. Ray AS, et al. Among authors: cheng yc. Antimicrob Agents Chemother. 2005 May;49(5):1994-2001. doi: 10.1128/AAC.49.5.1994-2001.2005. Antimicrob Agents Chemother. 2005. PMID: 15855524 Free PMC article.
Design and synthesis of 2',3'-dideoxy-2',3'-didehydro-beta-L-cytidine (beta-L-d4C) and 2',3'-dideoxy 2',3'-didehydro-beta-L-5-fluorocytidine (beta-L-Fd4C), two exceptionally potent inhibitors of human hepatitis B virus (HBV) and potent inhibitors of human immunodeficiency virus (HIV) in vitro.
Lin TS, Luo MZ, Liu MC, Zhu YL, Gullen E, Dutschman GE, Cheng YC. Lin TS, et al. Among authors: cheng yc. J Med Chem. 1996 Apr 26;39(9):1757-9. doi: 10.1021/jm950836q. J Med Chem. 1996. PMID: 8627596 No abstract available.
1,551 results