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Nonpeptidic HIV protease inhibitors: 4-hydroxy-pyran-2-one inhibitors with functional tethers to P1 phenyl ring to reach S3 pocket of the enzyme.
Vara Prasad J, Tummino PJ, Ferguson D, Saunders J, Vander Roest S, McQuade TJ, Heldsinger A, Reyner EL, Stewart BH, Guttendorf RJ, Para KS, Lunney EA, Gracheck SJ, Domagala JM. Vara Prasad J, et al. Among authors: guttendorf rj. Biochem Biophys Res Commun. 1996 Apr 25;221(3):815-20. doi: 10.1006/bbrc.1996.0679. Biochem Biophys Res Commun. 1996. PMID: 8630044
Genetic aspects of drug disposition and therapeutics.
Guttendorf RJ, Wedlund PJ. Guttendorf RJ, et al. J Clin Pharmacol. 1992 Feb;32(2):107-17. doi: 10.1002/j.1552-4604.1992.tb03814.x. J Clin Pharmacol. 1992. PMID: 1613119 Review. No abstract available.
Pharmacokinetics of clinafloxacin enantiomers in humans.
Humphrey GH, Shapiro MA, Randinitis EJ, Guttendorf RJ, Brodfuehrer JI. Humphrey GH, et al. Among authors: guttendorf rj. J Clin Pharmacol. 1999 Nov;39(11):1143-50. J Clin Pharmacol. 1999. PMID: 10579144
20 results