Heldsinger A - Search Results

1

Nonpeptidic HIV protease inhibitors: 4-hydroxy-pyran-2-one inhibitors with functional tethers to P1 phenyl ring to reach S3 pocket of the enzyme.

Vara Prasad J, Tummino PJ, Ferguson D, Saunders J, Vander Roest S, McQuade TJ, Heldsinger A, Reyner EL, Stewart BH, Guttendorf RJ, Para KS, Lunney EA, Gracheck SJ, Domagala JM. Vara Prasad J, et al. Among authors: heldsinger a. Biochem Biophys Res Commun. 1996 Apr 25;221(3):815-20. doi: 10.1006/bbrc.1996.0679. Biochem Biophys Res Commun. 1996. PMID: 8630044

2

Inhibition of the early phase of HIV replication by an isothiazolone, PD 161374.

Sharmeen L, McQuade T, Heldsinger A, Gogliotti R, Domagala J, Gracheck S. Sharmeen L, et al. Among authors: heldsinger a. Antiviral Res. 2001 Feb;49(2):101-14. doi: 10.1016/s0166-3542(00)00143-1. Antiviral Res. 2001. PMID: 11248362

3

An HIV-1 protease screening assay using a non-infectious proviral clone.

Heldsinger AA, Antonucci T. Heldsinger AA, et al. J Virol Methods. 1994 Oct;49(3):247-55. doi: 10.1016/0166-0934(94)90140-6. J Virol Methods. 1994. PMID: 7868643

4

Discovery of selective, small-molecule inhibitors of RNA complexes--I. The Tat protein/TAR RNA complexes required for HIV-1 transcription.

Mei HY, Mack DP, Galan AA, Halim NS, Heldsinger A, Loo JA, Moreland DW, Sannes-Lowery KA, Sharmeen L, Truong HN, Czarnik AW. Mei HY, et al. Among authors: heldsinger a. Bioorg Med Chem. 1997 Jun;5(6):1173-84. doi: 10.1016/s0968-0896(97)00064-3. Bioorg Med Chem. 1997. PMID: 9222511

5

Inhibitors of protein-RNA complexation that target the RNA: specific recognition of human immunodeficiency virus type 1 TAR RNA by small organic molecules.

Mei HY, Cui M, Heldsinger A, Lemrow SM, Loo JA, Sannes-Lowery KA, Sharmeen L, Czarnik AW. Mei HY, et al. Among authors: heldsinger a. Biochemistry. 1998 Oct 6;37(40):14204-12. doi: 10.1021/bi981308u. Biochemistry. 1998. PMID: 9760258

6

Functional reconstitution of lost activity of chemically cross-linked or mutant moloney murine leukemia virus nucleocapsid proteins by trans-complementation.

Heldsinger A, Sharmeen L. Heldsinger A, et al. Arch Virol. 2001 Dec;146(12):2385-400. doi: 10.1007/s007050170010. Arch Virol. 2001. PMID: 11811687

7

Erythromycin contracts rabbit colon myocytes via occupation of motilin receptors.

Hasler WL, Heldsinger A, Chung OY. Hasler WL, et al. Among authors: heldsinger a. Am J Physiol. 1992 Jan;262(1 Pt 1):G50-5. doi: 10.1152/ajpgi.1992.262.1.G50. Am J Physiol. 1992. PMID: 1733270

8

Synergistic interaction between leptin and cholecystokinin in the rat nodose ganglia is mediated by PI3K and STAT3 signaling pathways: implications for leptin as a regulator of short term satiety.

Heldsinger A, Grabauskas G, Song I, Owyang C. Heldsinger A, et al. J Biol Chem. 2011 Apr 1;286(13):11707-15. doi: 10.1074/jbc.M110.198945. Epub 2011 Jan 26. J Biol Chem. 2011. PMID: 21270124 Free PMC article.

9

Ghrelin induces leptin resistance by activation of suppressor of cytokine signaling 3 expression in male rats: implications in satiety regulation.

Heldsinger A, Grabauskas G, Wu X, Zhou S, Lu Y, Song I, Owyang C. Heldsinger A, et al. Endocrinology. 2014 Oct;155(10):3956-69. doi: 10.1210/en.2013-2095. Epub 2014 Jul 25. Endocrinology. 2014. PMID: 25060362 Free PMC article.

10

Cisapride acts on muscarinic (glandular M2) receptors to induce contraction of isolated gastric myocytes: mediation via a calcium-phosphoinositide pathway.

Hasler WL, Heldsinger A, Owyang C. Hasler WL, et al. Among authors: heldsinger a. J Pharmacol Exp Ther. 1991 Dec;259(3):1294-300. J Pharmacol Exp Ther. 1991. PMID: 1662275

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