O'Connor PM - Search Results

1

An abnormality in the p53 pathway following gamma-irradiation in many wild-type p53 human melanoma lines.

Bae I, Smith ML, Sheikh MS, Zhan Q, Scudiero DA, Friend SH, O'Connor PM, Fornace AJ Jr. Bae I, et al. Cancer Res. 1996 Feb 15;56(4):840-7. Cancer Res. 1996. PMID: 8631022

2

Disruption of p53 function sensitizes breast cancer MCF-7 cells to cisplatin and pentoxifylline.

Fan S, Smith ML, Rivet DJ 2nd, Duba D, Zhan Q, Kohn KW, Fornace AJ Jr, O'Connor PM. Fan S, et al. Cancer Res. 1995 Apr 15;55(8):1649-54. Cancer Res. 1995. PMID: 7712469

3

Relationships between G1 arrest and stability of the p53 and p21Cip1/Waf1 proteins following gamma-irradiation of human lymphoma cells.

Bae I, Fan S, Bhatia K, Kohn KW, Fornace AJ Jr, O'Connor PM. Bae I, et al. Cancer Res. 1995 Jun 1;55(11):2387-93. Cancer Res. 1995. PMID: 7757991

4

p53 gene mutations are associated with decreased sensitivity of human lymphoma cells to DNA damaging agents.

Fan S, el-Deiry WS, Bae I, Freeman J, Jondle D, Bhatia K, Fornace AJ Jr, Magrath I, Kohn KW, O'Connor PM. Fan S, et al. Cancer Res. 1994 Nov 15;54(22):5824-30. Cancer Res. 1994. PMID: 7954409

5

Induction of bax by genotoxic stress in human cells correlates with normal p53 status and apoptosis.

Zhan Q, Fan S, Bae I, Guillouf C, Liebermann DA, O'Connor PM, Fornace AJ Jr. Zhan Q, et al. Oncogene. 1994 Dec;9(12):3743-51. Oncogene. 1994. PMID: 7970735

6

Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen.

Smith ML, Chen IT, Zhan Q, Bae I, Chen CY, Gilmer TM, Kastan MB, O'Connor PM, Fornace AJ Jr. Smith ML, et al. Science. 1994 Nov 25;266(5189):1376-80. doi: 10.1126/science.7973727. Science. 1994. PMID: 7973727

7

Abrogation of p53 function affects gadd gene responses to DNA base-damaging agents and starvation.

Zhan Q, Fan S, Smith ML, Bae I, Yu K, Alamo I Jr, O'Connor PM, Fornace AJ Jr. Zhan Q, et al. DNA Cell Biol. 1996 Oct;15(10):805-15. doi: 10.1089/dna.1996.15.805. DNA Cell Biol. 1996. PMID: 8892753

8

Antisense GADD45 expression results in decreased DNA repair and sensitizes cells to u.v.-irradiation or cisplatin.

Smith ML, Kontny HU, Zhan Q, Sreenath A, O'Connor PM, Fornace AJ Jr. Smith ML, et al. Oncogene. 1996 Nov 21;13(10):2255-63. Oncogene. 1996. PMID: 8950993

9

Characterization of the p53 tumor suppressor pathway in cell lines of the National Cancer Institute anticancer drug screen and correlations with the growth-inhibitory potency of 123 anticancer agents.

O'Connor PM, Jackman J, Bae I, Myers TG, Fan S, Mutoh M, Scudiero DA, Monks A, Sausville EA, Weinstein JN, Friend S, Fornace AJ Jr, Kohn KW. O'Connor PM, et al. Cancer Res. 1997 Oct 1;57(19):4285-300. Cancer Res. 1997. PMID: 9331090

10

Inactivation of p53 increases the cytotoxicity of camptothecin in human colon HCT116 and breast MCF-7 cancer cells.

Gupta M, Fan S, Zhan Q, Kohn KW, O'Connor PM, Pommier Y. Gupta M, et al. Clin Cancer Res. 1997 Sep;3(9):1653-60. Clin Cancer Res. 1997. PMID: 9815856

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