Ward RW - Search Results

1

Structure-based design of lipophilic quinazoline inhibitors of thymidylate synthase.

Jones TR, Varney MD, Webber SE, Lewis KK, Marzoni GP, Palmer CL, Kathardekar V, Welsh KM, Webber S, Matthews DA, Appelt K, Smith WW, Janson CA, Villafranca JE, Bacquet RJ, Howland EF, Booth CL, Herrmann SM, Ward RW, White J, Moomaw EW, Bartlett CA, Morse CA. Jones TR, et al. Among authors: ward rw. J Med Chem. 1996 Feb 16;39(4):904-17. doi: 10.1021/jm9502652. J Med Chem. 1996. PMID: 8632414

2

Structure-based design of substituted diphenyl sulfones and sulfoxides as lipophilic inhibitors of thymidylate synthase.

Jones TR, Webber SE, Varney MD, Reddy MR, Lewis KK, Kathardekar V, Mazdiyasni H, Deal J, Nguyen D, Welsh KM, Webber S, Johnston A, Matthews DA, Smith WW, Janson CA, Bacquet RJ, Howland EF, Booth CL, Herrmann SM, Ward RW, White J, Bartlett CA, Morse CA. Jones TR, et al. Among authors: ward rw. J Med Chem. 1997 Feb 28;40(5):677-83. doi: 10.1021/jm960613f. J Med Chem. 1997. PMID: 9057854

3

Synthesis of novel N-phosphonoalkyl dipeptide inhibitors of human collagenase.

Bird J, De Mello RC, Harper GP, Hunter DJ, Karran EH, Markwell RE, Miles-Williams AJ, Rahman SS, Ward RW. Bird J, et al. Among authors: ward rw. J Med Chem. 1994 Jan 7;37(1):158-69. doi: 10.1021/jm00027a020. J Med Chem. 1994. PMID: 8289190

4

3-Anilino-4-arylmaleimides: potent and selective inhibitors of glycogen synthase kinase-3 (GSK-3).

Smith DG, Buffet M, Fenwick AE, Haigh D, Ife RJ, Saunders M, Slingsby BP, Stacey R, Ward RW. Smith DG, et al. Among authors: ward rw. Bioorg Med Chem Lett. 2001 Mar 12;11(5):635-9. doi: 10.1016/s0960-894x(00)00721-6. Bioorg Med Chem Lett. 2001. PMID: 11266159

5

Evaluation of a series of anticonvulsant 1,2,3,4-tetrahydroisoquinolinyl-benzamides.

Chan WN, Hadley MS, Harling JD, Herdon HJ, Orlek BS, Riley GJ, Stead RE, Stean TO, Thompson M, Upton N, Ward RW. Chan WN, et al. Among authors: ward rw. Bioorg Med Chem. 2000 Aug;8(8):2085-94. doi: 10.1016/s0968-0896(00)00149-8. Bioorg Med Chem. 2000. PMID: 11003154

6

Identification of a series of 1,2,3,4-tetrahydroisoquinolinyl-benzamides with potential anticonvulsant activity.

Chan WN, Hadley MS, Harling JD, Herdon HJ, Jerman JC, Orlek BS, Stean TO, Thompson M, Upton N, Ward RW. Chan WN, et al. Among authors: ward rw. Bioorg Med Chem Lett. 1998 Oct 20;8(20):2903-6. doi: 10.1016/s0960-894x(98)00523-x. Bioorg Med Chem Lett. 1998. PMID: 9873645

7

5-aryl-pyrazolo[3,4-b]pyridines: potent inhibitors of glycogen synthase kinase-3 (GSK-3).

Witherington J, Bordas V, Garland SL, Hickey DM, Ife RJ, Liddle J, Saunders M, Smith DG, Ward RW. Witherington J, et al. Among authors: ward rw. Bioorg Med Chem Lett. 2003 May 5;13(9):1577-80. doi: 10.1016/s0960-894x(03)00134-3. Bioorg Med Chem Lett. 2003. PMID: 12699759

8

6-aryl-pyrazolo[3,4-b]pyridines: potent inhibitors of glycogen synthase kinase-3 (GSK-3).

Witherington J, Bordas V, Gaiba A, Garton NS, Naylor A, Rawlings AD, Slingsby BP, Smith DG, Takle AK, Ward RW. Witherington J, et al. Among authors: ward rw. Bioorg Med Chem Lett. 2003 Sep 15;13(18):3055-7. doi: 10.1016/s0960-894x(03)00645-0. Bioorg Med Chem Lett. 2003. PMID: 12941332

9

5-aryl-pyrazolo[3,4-b]pyridazines: potent inhibitors of glycogen synthase kinase-3 (GSK-3).

Witherington J, Bordas V, Haigh D, Hickey DM, Ife RJ, Rawlings AD, Slingsby BP, Smith DG, Ward RW. Witherington J, et al. Among authors: ward rw. Bioorg Med Chem Lett. 2003 May 5;13(9):1581-4. doi: 10.1016/s0960-894x(03)00135-5. Bioorg Med Chem Lett. 2003. PMID: 12699760

10

6-heteroaryl-pyrazolo[3,4-b]pyridines: potent and selective inhibitors of glycogen synthase kinase-3 (GSK-3).

Witherington J, Bordas V, Gaiba A, Naylor A, Rawlings AD, Slingsby BP, Smith DG, Takle AK, Ward RW. Witherington J, et al. Among authors: ward rw. Bioorg Med Chem Lett. 2003 Sep 15;13(18):3059-62. doi: 10.1016/s0960-894x(03)00646-2. Bioorg Med Chem Lett. 2003. PMID: 12941333

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