Greytok JA - Search Results

1

Aminodiol HIV protease inhibitors. Synthesis and structure-activity relationships of P1/P1' compounds: correlation between lipophilicity and cytotoxicity.

Chen P, Cheng PT, Alam M, Beyer BD, Bisacchi GS, Dejneka T, Evans AJ, Greytok JA, Hermsmeier MA, Humphreys WG, Jacobs GA, Kocy O, Lin PF, Lis KA, Marella MA, Ryono DE, Sheaffer AK, Spergel SH, Sun CQ, Tino JA, Vite G, Colonno RJ, Zahler R, Barrish JC. Chen P, et al. Among authors: greytok ja. J Med Chem. 1996 May 10;39(10):1991-2007. doi: 10.1021/jm950717a. J Med Chem. 1996. PMID: 8642558

2

Aminodiol HIV protease inhibitors. 1. Design, synthesis, and preliminary SAR.

Barrish JC, Gordon E, Alam M, Lin PF, Bisacchi GS, Chen P, Cheng PT, Fritz AW, Greytok JA, Hermsmeier MA. Barrish JC, et al. Among authors: greytok ja. J Med Chem. 1994 Jun 10;37(12):1758-68. doi: 10.1021/jm00038a005. J Med Chem. 1994. PMID: 8021916

3

Antiviral properties of aminodiol inhibitors against human immunodeficiency virus and protease.

Bechtold CM, Patick AK, Alam M, Greytok J, Tino JA, Chen P, Gordon E, Ahmad S, Barrish JC, Zahler R, et al. Bechtold CM, et al. Among authors: greytok j. Antimicrob Agents Chemother. 1995 Feb;39(2):374-9. doi: 10.1128/AAC.39.2.374. Antimicrob Agents Chemother. 1995. PMID: 7726501 Free PMC article.

4

Characterization of a human immunodeficiency virus type 1 variant with reduced sensitivity to an aminodiol protease inhibitor.

Patick AK, Rose R, Greytok J, Bechtold CM, Hermsmeier MA, Chen PT, Barrish JC, Zahler R, Colonno RJ, Lin PF. Patick AK, et al. J Virol. 1995 Apr;69(4):2148-52. doi: 10.1128/JVI.69.4.2148-2152.1995. J Virol. 1995. PMID: 7884862 Free PMC article.

5

Human immunodeficiency virus type 1 viral background plays a major role in development of resistance to protease inhibitors.

Rose RE, Gong YF, Greytok JA, Bechtold CM, Terry BJ, Robinson BS, Alam M, Colonno RJ, Lin PF. Rose RE, et al. Among authors: greytok ja. Proc Natl Acad Sci U S A. 1996 Feb 20;93(4):1648-53. doi: 10.1073/pnas.93.4.1648. Proc Natl Acad Sci U S A. 1996. PMID: 8643685 Free PMC article.

6

Rencofilstat, a cyclophilin inhibitor: A phase 2a, multicenter, single-blind, placebo-controlled study in F2/F3 NASH.

Harrison SA, Mayo PR, Hobbs TM, Canizares C, Foster EP, Zhao C, Ure DR, Trepanier DJ, Greytok JA, Foster RT. Harrison SA, et al. Among authors: greytok ja. Hepatol Commun. 2022 Dec;6(12):3379-3392. doi: 10.1002/hep4.2100. Epub 2022 Oct 22. Hepatol Commun. 2022. PMID: 36271849 Free PMC article. Clinical Trial.

7

Effect of a High-Fat Meal on Single-Dose Rencofilstat (CRV431) Oral Bioavailability in Healthy Human Subjects.

Remenchik E, Mayo PR, Hobbs TM, Greytok JA, Foster EP, Zhao C, Ure D, Trepanier DJ, Foster RT. Remenchik E, et al. Among authors: greytok ja. Clin Pharmacol Drug Dev. 2023 Mar;12(3):287-293. doi: 10.1002/cpdd.1179. Epub 2022 Oct 17. Clin Pharmacol Drug Dev. 2023. PMID: 36251165 Clinical Trial.

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