Enzymic activities of two-chain pepsinogen, two-chain pepsin, and the amino-terminal lobe of pepsinogen.
Lin XL, Lin YZ, Koelsch G, Gustchina A, Wlodawer A, Tang J.
Lin XL, et al. Among authors: tang j.
J Biol Chem. 1992 Aug 25;267(24):17257-63.
J Biol Chem. 1992.
PMID: 1512263
Free article.
It has been postulated that mammalian aspartic proteases, which contain two structurally homologous lobes, are derived in evolution from a homodimer enzyme by gene duplication and fusion (Tang, J., James, M. N. G., Hsu, I.-N., Jenkins, J. A., and Blundell, T. …
It has been postulated that mammalian aspartic proteases, which contain two structurally homologous lobes, are derived in evolution from a h …