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Restoration of serine protease-inhibitor interaction by protein engineering.
Madison EL, Goldsmith EJ, Gething MJ, Sambrook JF, Gerard RD. Madison EL, et al. Among authors: goldsmith ej. J Biol Chem. 1990 Dec 15;265(35):21423-6. J Biol Chem. 1990. PMID: 2123870 Free article.
We have previously demonstrated that mutation of arginine 304 of t-PA to a glutamic acid residue drastically reduces the rate of interaction between the enzyme and its suicide substrate, PAI-1, without affecting the reactivity of the enzyme toward its normal substrate, plasminoge …
We have previously demonstrated that mutation of arginine 304 of t-PA to a glutamic acid residue drastically reduces the rate of interaction …
Protein kinases.
Goldsmith EJ, Cobb MH. Goldsmith EJ, et al. Curr Opin Struct Biol. 1994 Dec;4(6):833-40. doi: 10.1016/0959-440x(94)90264-x. Curr Opin Struct Biol. 1994. PMID: 7712287 Review.
How MAP kinases are regulated.
Cobb MH, Goldsmith EJ. Cobb MH, et al. Among authors: goldsmith ej. J Biol Chem. 1995 Jun 23;270(25):14843-6. doi: 10.1074/jbc.270.25.14843. J Biol Chem. 1995. PMID: 7797459 Free article. Review. No abstract available.
302 results