Kelson AB - Search Results

1

The pharmacokinetics, bioavailability and biodistribution in mice of a rationally designed 2-nitroimidazole hypoxia probe SR-4554.

Aboagye EO, Lewis AD, Graham MA, Tracy M, Kelson AB, Ryan KJ, Workman P. Aboagye EO, et al. Among authors: kelson ab. Anticancer Drug Des. 1996 Apr;11(3):231-42. Anticancer Drug Des. 1996. PMID: 8663910

2

Development and validation of a solid-phase extraction and high-performance liquid chromatographic assay for a novel fluorinated 2-nitroimidazole hypoxia probe (SR-4554) in Balb/c mouse plasma.

Aboagye EO, Graham MA, Lewis AD, Workman P, Kelson AB, Tracy M. Aboagye EO, et al. Among authors: kelson ab. J Chromatogr B Biomed Appl. 1995 Oct 6;672(1):125-32. doi: 10.1016/0378-4347(95)00204-v. J Chromatogr B Biomed Appl. 1995. PMID: 8590924

3

Preclinical evaluation of the fluorinated 2-nitroimidazole N-(2-hydroxy-3,3,3-trifluoropropyl)-2-(2-nitro-1-imidazolyl) acetamide (SR-4554) as a probe for the measurement of tumor hypoxia.

Aboagye EO, Maxwell RJ, Kelson AB, Tracy M, Lewis AD, Graham MA, Horsman MR, Griffiths JR, Workman P. Aboagye EO, et al. Among authors: kelson ab. Cancer Res. 1997 Aug 1;57(15):3314-8. Cancer Res. 1997. PMID: 9242466

4

Preclinical development and current status of the fluorinated 2-nitroimidazole hypoxia probe N-(2-hydroxy-3,3,3-trifluoropropyl)-2-(2-nitro-1-imidazolyl) acetamide (SR 4554, CRC 94/17): a non-invasive diagnostic probe for the measurement of tumor hypoxia by magnetic resonance spectroscopy and imaging, and by positron emission tomography.

Aboagye EO, Kelson AB, Tracy M, Workman P. Aboagye EO, et al. Among authors: kelson ab. Anticancer Drug Des. 1998 Sep;13(6):703-30. Anticancer Drug Des. 1998. PMID: 9755726 Review.

5

1,2,4-Benzotriazine 1,4-dioxides. An important class of hypoxic cytotoxins with antitumor activity.

Kelson AB, McNamara JP, Pandey A, Ryan KJ, Dorie MJ, McAfee PA, Menke DR, Brown JM, Tracy M. Kelson AB, et al. Anticancer Drug Des. 1998 Sep;13(6):575-92. Anticancer Drug Des. 1998. PMID: 9755719

6

Quaternary salts of 2-[(hydroxyimino)methyl]imidazole. 4. Effect of various side-chain substituents on therapeutic activity against anticholinesterase intoxication.

Goff DA, Koolpe GA, Kelson AB, Vu HM, Taylor DL, Bedford CD, Musallam HA, Koplovitz I, Harris RN 3rd. Goff DA, et al. Among authors: kelson ab. J Med Chem. 1991 Apr;34(4):1363-8. doi: 10.1021/jm00108a019. J Med Chem. 1991. PMID: 2016711

7

Characterization of opiates, neuroleptics, and synthetic analogs at ORL1 and opioid receptors.

Zaveri N, Polgar WE, Olsen CM, Kelson AB, Grundt P, Lewis JW, Toll L. Zaveri N, et al. Among authors: kelson ab. Eur J Pharmacol. 2001 Sep 28;428(1):29-36. doi: 10.1016/s0014-2999(01)01282-1. Eur J Pharmacol. 2001. PMID: 11779034 Free PMC article.

8

Ovarian sex steroid-dependent plasticity of nociceptin/orphanin FQ and opioid modulation of spinal dynorphin release.

Gupta DS, Kelson AB, Polgar WE, Toll L, Szücs M, Gintzler AR. Gupta DS, et al. Among authors: kelson ab. J Pharmacol Exp Ther. 2001 Sep;298(3):1213-20. J Pharmacol Exp Ther. 2001. PMID: 11504823

9

Antitumor efficacy and molecular mechanism of TLK58747, a novel DNA-alkylating prodrug.

Xu H, Wang Z, Donaldson JC, Yao H, Zhou S, Kelson AB, Ma W, Weber KT, Laborde E, Cheng M, Sambucetti L, Keck JG. Xu H, et al. Among authors: kelson ab. Anticancer Res. 2009 Oct;29(10):3845-55. Anticancer Res. 2009. PMID: 19846918 Free article.

10

Efficient synthesis of trisubstituted pyrazoles and isoxazoles using a traceless "catch and release" solid-phase strategy.

Ma W, Peterson B, Kelson A, Laborde E. Ma W, et al. J Comb Chem. 2009 Jul-Aug;11(4):697-703. doi: 10.1021/cc900045t. J Comb Chem. 2009. PMID: 19459688

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