O'Shea JJ - Search Results

1

In vitro correction of JAK3-deficient severe combined immunodeficiency by retroviral-mediated gene transduction.

Candotti F, Oakes SA, Johnston JA, Notarangelo LD, O'Shea JJ, Blaese RM. Candotti F, et al. J Exp Med. 1996 Jun 1;183(6):2687-92. doi: 10.1084/jem.183.6.2687. J Exp Med. 1996. PMID: 8676091 Free PMC article.

2

Mutation of Jak3 in a patient with SCID: essential role of Jak3 in lymphoid development.

Russell SM, Tayebi N, Nakajima H, Riedy MC, Roberts JL, Aman MJ, Migone TS, Noguchi M, Markert ML, Buckley RH, O'Shea JJ, Leonard WJ. Russell SM, et al. Science. 1995 Nov 3;270(5237):797-800. doi: 10.1126/science.270.5237.797. Science. 1995. PMID: 7481768

3

Interleukins 2, 4, 7, and 15 stimulate tyrosine phosphorylation of insulin receptor substrates 1 and 2 in T cells. Potential role of JAK kinases.

Johnston JA, Wang LM, Hanson EP, Sun XJ, White MF, Oakes SA, Pierce JH, O'Shea JJ. Johnston JA, et al. J Biol Chem. 1995 Dec 1;270(48):28527-30. doi: 10.1074/jbc.270.48.28527. J Biol Chem. 1995. PMID: 7499365 Free article.

4

Analysis of interleukin-2-dependent signal transduction through the Shc/Grb2 adapter pathway. Interleukin-2-dependent mitogenesis does not require Shc phosphorylation or receptor association.

Evans GA, Goldsmith MA, Johnston JA, Xu W, Weiler SR, Erwin R, Howard OM, Abraham RT, O'Shea JJ, Greene WC, et al. Evans GA, et al. J Biol Chem. 1995 Dec 1;270(48):28858-63. doi: 10.1074/jbc.270.48.28858. J Biol Chem. 1995. PMID: 7499411 Free article.

5

Interleukin 12 (IL-12) induces tyrosine phosphorylation of JAK2 and TYK2: differential use of Janus family tyrosine kinases by IL-2 and IL-12.

Bacon CM, McVicar DW, Ortaldo JR, Rees RC, O'Shea JJ, Johnston JA. Bacon CM, et al. J Exp Med. 1995 Jan 1;181(1):399-404. doi: 10.1084/jem.181.1.399. J Exp Med. 1995. PMID: 7528775 Free PMC article.

6

Regulation of JAK3 expression in human monocytes: phosphorylation in response to interleukins 2, 4, and 7.

Musso T, Johnston JA, Linnekin D, Varesio L, Rowe TK, O'Shea JJ, McVicar DW. Musso T, et al. J Exp Med. 1995 Apr 1;181(4):1425-31. doi: 10.1084/jem.181.4.1425. J Exp Med. 1995. PMID: 7535338 Free PMC article.

7

Keegan AD, Johnston JA, Tortolani PJ, McReynolds LJ, Kinzer C, O'Shea JJ, Paul WE. Keegan AD, et al. Proc Natl Acad Sci U S A. 1995 Aug 15;92(17):7681-5. doi: 10.1073/pnas.92.17.7681. Proc Natl Acad Sci U S A. 1995. PMID: 7544000 Free PMC article.

8

Regulation of JAK3 expression and activation in human B cells and B cell malignancies.

Tortolani PJ, Lal BK, Riva A, Johnston JA, Chen YQ, Reaman GH, Beckwith M, Longo D, Ortaldo JR, Bhatia K, McGrath I, Kehrl J, Tuscano J, McVicar DW, O'Shea JJ. Tortolani PJ, et al. J Immunol. 1995 Dec 1;155(11):5220-6. J Immunol. 1995. PMID: 7594533

9

Interleukin 12 induces tyrosine phosphorylation and activation of STAT4 in human lymphocytes.

Bacon CM, Petricoin EF 3rd, Ortaldo JR, Rees RC, Larner AC, Johnston JA, O'Shea JJ. Bacon CM, et al. Proc Natl Acad Sci U S A. 1995 Aug 1;92(16):7307-11. doi: 10.1073/pnas.92.16.7307. Proc Natl Acad Sci U S A. 1995. PMID: 7638186 Free PMC article.

10

Mutations of Jak-3 gene in patients with autosomal severe combined immune deficiency (SCID).

Macchi P, Villa A, Giliani S, Sacco MG, Frattini A, Porta F, Ugazio AG, Johnston JA, Candotti F, O'Shea JJ, et al. Macchi P, et al. Nature. 1995 Sep 7;377(6544):65-8. doi: 10.1038/377065a0. Nature. 1995. PMID: 7659163

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