O'Rourke K - Search Results

1

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex.

Muzio M, Chinnaiyan AM, Kischkel FC, O'Rourke K, Shevchenko A, Ni J, Scaffidi C, Bretz JD, Zhang M, Gentz R, Mann M, Krammer PH, Peter ME, Dixit VM. Muzio M, et al. Cell. 1996 Jun 14;85(6):817-27. doi: 10.1016/s0092-8674(00)81266-0. Cell. 1996. PMID: 8681377 Free article.

2

FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis.

Chinnaiyan AM, O'Rourke K, Tewari M, Dixit VM. Chinnaiyan AM, et al. Cell. 1995 May 19;81(4):505-12. doi: 10.1016/0092-8674(95)90071-3. Cell. 1995. PMID: 7538907 Free article.

3

Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase.

Tewari M, Quan LT, O'Rourke K, Desnoyers S, Zeng Z, Beidler DR, Poirier GG, Salvesen GS, Dixit VM. Tewari M, et al. Cell. 1995 Jun 2;81(5):801-9. doi: 10.1016/0092-8674(95)90541-3. Cell. 1995. PMID: 7774019 Free article.

4

Molecular ordering of the cell death pathway. Bcl-2 and Bcl-xL function upstream of the CED-3-like apoptotic proteases.

Chinnaiyan AM, Orth K, O'Rourke K, Duan H, Poirier GG, Dixit VM. Chinnaiyan AM, et al. J Biol Chem. 1996 Mar 1;271(9):4573-6. doi: 10.1074/jbc.271.9.4573. J Biol Chem. 1996. PMID: 8617712 Free article.

5

FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis.

Chinnaiyan AM, Tepper CG, Seldin MF, O'Rourke K, Kischkel FC, Hellbardt S, Krammer PH, Peter ME, Dixit VM. Chinnaiyan AM, et al. J Biol Chem. 1996 Mar 1;271(9):4961-5. doi: 10.1074/jbc.271.9.4961. J Biol Chem. 1996. PMID: 8617770 Free article.

6

Molecular ordering of apoptotic mammalian CED-3/ICE-like proteases.

Orth K, O'Rourke K, Salvesen GS, Dixit VM. Orth K, et al. J Biol Chem. 1996 Aug 30;271(35):20977-80. doi: 10.1074/jbc.271.35.20977. J Biol Chem. 1996. PMID: 8702858 Free article.

7

Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95.

Chinnaiyan AM, O'Rourke K, Yu GL, Lyons RH, Garg M, Duan DR, Xing L, Gentz R, Ni J, Dixit VM. Chinnaiyan AM, et al. Science. 1996 Nov 8;274(5289):990-2. doi: 10.1126/science.274.5289.990. Science. 1996. PMID: 8875942

8

Interaction of CED-4 with CED-3 and CED-9: a molecular framework for cell death.

Chinnaiyan AM, O'Rourke K, Lane BR, Dixit VM. Chinnaiyan AM, et al. Science. 1997 Feb 21;275(5303):1122-6. doi: 10.1126/science.275.5303.1122. Science. 1997. PMID: 9027312

9

The receptor for the cytotoxic ligand TRAIL.

Pan G, O'Rourke K, Chinnaiyan AM, Gentz R, Ebner R, Ni J, Dixit VM. Pan G, et al. Science. 1997 Apr 4;276(5309):111-3. doi: 10.1126/science.276.5309.111. Science. 1997. PMID: 9082980

10

The death inhibitory molecules CED-9 and CED-4L use a common mechanism to inhibit the CED-3 death protease.

Chaudhary D, O'Rourke K, Chinnaiyan AM, Dixit VM. Chaudhary D, et al. J Biol Chem. 1998 Jul 10;273(28):17708-12. doi: 10.1074/jbc.273.28.17708. J Biol Chem. 1998. PMID: 9651369 Free article.

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