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A dopaminergic neurotoxin, 1(R), 2(N)-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, N-methyl(R)salsolinol, and its oxidation product, 1,2(N)-dimethyl-6,7-dihydroxyisoquinolinium ion, accumulate in the nigro-striatal system of the human brain.
Maruyama W, Sobue G, Matsubara K, Hashizume Y, Dostert P, Naoi M. Maruyama W, et al. Among authors: dostert p. Neurosci Lett. 1997 Feb 14;223(1):61-4. doi: 10.1016/s0304-3940(97)13389-4. Neurosci Lett. 1997. PMID: 9058423
Assay for the (R)- and (S)-enantiomers of salsolinols in biological samples and foods with ion-pair high-performance liquid chromatography using beta-cyclodextrin as a chiral mobile phase additive.
Deng Y, Maruyama W, Kawai M, Dostert P, Yamamura H, Takahashi T, Naoi M. Deng Y, et al. Among authors: dostert p. J Chromatogr B Biomed Sci Appl. 1997 Feb 21;689(2):313-20. doi: 10.1016/s0378-4347(96)00359-3. J Chromatogr B Biomed Sci Appl. 1997. PMID: 9080316
Endogenous synthesis of N-methylsalsolinol, an analogue of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, in rat brain during in vivo microdialysis with salsolinol, as demonstrated by gas chromatography-mass spectrometry.
Niwa T, Maruyama W, Nakahara D, Takeda N, Yoshizumi H, Tatematsu A, Takahashi A, Dostert P, Naoi M, Nagatsu T. Niwa T, et al. Among authors: dostert p. J Chromatogr. 1992 Jul 1;578(1):109-15. doi: 10.1016/0378-4347(92)80231-e. J Chromatogr. 1992. PMID: 1400775
121 results