Reczek PR - Search Results

1

Retinoic acid receptor beta,gamma-selective ligands: synthesis and biological activity of 6-substituted 2-naphthoic acid retinoids.

Yu KL, Spinazze P, Ostrowski J, Currier SJ, Pack EJ, Hammer L, Roalsvig T, Honeyman JA, Tortolani DR, Reczek PR, Mansuri MM, Starrett JE Jr. Yu KL, et al. Among authors: reczek pr. J Med Chem. 1996 Jun 7;39(12):2411-21. doi: 10.1021/jm9502293. J Med Chem. 1996. PMID: 8691435

2

The N-terminal portion of domain E of retinoic acid receptors alpha and beta is essential for the recognition of retinoic acid and various analogs.

Ostrowski J, Hammer L, Roalsvig T, Pokornowski K, Reczek PR. Ostrowski J, et al. Among authors: reczek pr. Proc Natl Acad Sci U S A. 1995 Mar 14;92(6):1812-6. doi: 10.1073/pnas.92.6.1812. Proc Natl Acad Sci U S A. 1995. PMID: 7892182 Free PMC article.

3

Role of retinoic acid receptor gamma in the Rhino mouse and rabbit irritation models of retinoid activity.

Reczek PR, Ostrowski J, Yu KL, Chen S, Hammer L, Roalsvig T, Starrett JE Jr, Driscoll JP, Whiting G, Spinazze PG, et al. Reczek PR, et al. Skin Pharmacol. 1995;8(6):292-9. doi: 10.1159/000211360. Skin Pharmacol. 1995. PMID: 8688195

4

Serine 232 and methionine 272 define the ligand binding pocket in retinoic acid receptor subtypes.

Ostrowski J, Roalsvig T, Hammer L, Marinier A, Starrett JE Jr, Yu KL, Reczek PR. Ostrowski J, et al. Among authors: reczek pr. J Biol Chem. 1998 Feb 6;273(6):3490-5. doi: 10.1074/jbc.273.6.3490. J Biol Chem. 1998. PMID: 9452473 Free article.

5

Two distinct actions of retinoid-receptor ligands.

Chen JY, Clifford J, Zusi C, Starrett J, Tortolani D, Ostrowski J, Reczek PR, Chambon P, Gronemeyer H. Chen JY, et al. Among authors: reczek pr. Nature. 1996 Aug 29;382(6594):819-22. doi: 10.1038/382819a0. Nature. 1996. PMID: 8752277

6

Inhibition of disease progression by a novel retinoid antagonist in animal models of arthritis.

Beehler BC, Hei YJ, Chen S, Lupisella JA, Ostrowski J, Starrett JE, Tortolani D, Tramposch KM, Reczek PR. Beehler BC, et al. Among authors: reczek pr. J Rheumatol. 2003 Feb;30(2):355-63. J Rheumatol. 2003. PMID: 12563696

7

RAR-specific agonist/antagonists which dissociate transactivation and AP1 transrepression inhibit anchorage-independent cell proliferation.

Chen JY, Penco S, Ostrowski J, Balaguer P, Pons M, Starrett JE, Reczek P, Chambon P, Gronemeyer H. Chen JY, et al. EMBO J. 1995 Mar 15;14(6):1187-97. doi: 10.1002/j.1460-2075.1995.tb07102.x. EMBO J. 1995. PMID: 7720709 Free PMC article.

8

Retinoic acid receptor antagonist BMS453 inhibits the growth of normal and malignant breast cells without activating RAR-dependent gene expression.

Yang L, Munoz-Medellin D, Kim HT, Ostrowski J, Reczek P, Brown PH. Yang L, et al. Breast Cancer Res Treat. 1999 Aug;56(3):277-91. doi: 10.1023/a:1006219411078. Breast Cancer Res Treat. 1999. PMID: 10573118

9

The retinoic acid receptor antagonist, BMS453, inhibits normal breast cell growth by inducing active TGFbeta and causing cell cycle arrest.

Yang L, Ostrowski J, Reczek P, Brown P. Yang L, et al. Oncogene. 2001 Nov 29;20(55):8025-35. doi: 10.1038/sj.onc.1204911. Oncogene. 2001. PMID: 11753686

10

The ligand binding domain of the human retinoic acid receptor gamma is predominantly alpha-helical with a Trp residue in the ligand binding site.

Lupisella JA, Driscoll JE, Metzler WJ, Reczek PR. Lupisella JA, et al. Among authors: reczek pr. J Biol Chem. 1995 Oct 20;270(42):24884-90. doi: 10.1074/jbc.270.42.24884. J Biol Chem. 1995. PMID: 7559612 Free article.

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