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Somatic mutations causing constitutive activity of the thyrotropin receptor are the major cause of hyperfunctioning thyroid adenomas: identification of additional mutations activating both the cyclic adenosine 3',5'-monophosphate and inositol phosphate-Ca2+ cascades.
Parma J, Van Sande J, Swillens S, Tonacchera M, Dumont J, Vassart G. Parma J, et al. Among authors: tonacchera m. Mol Endocrinol. 1995 Jun;9(6):725-33. doi: 10.1210/mend.9.6.8592518. Mol Endocrinol. 1995. PMID: 8592518
TSH receptor and disease.
Tonacchera M, Van Sande J, Parma J, Duprez L, Cetani F, Costagliola S, Dumont JE, Vassart G. Tonacchera M, et al. Clin Endocrinol (Oxf). 1996 Jun;44(6):621-33. doi: 10.1046/j.1365-2265.1996.746567.x. Clin Endocrinol (Oxf). 1996. PMID: 8759174 Review. No abstract available.
Somatic and germline mutations of the TSH receptor gene in thyroid diseases.
Van Sande J, Parma J, Tonacchera M, Swillens S, Dumont J, Vassart G. Van Sande J, et al. Among authors: tonacchera m. J Clin Endocrinol Metab. 1995 Sep;80(9):2577-85. doi: 10.1210/jcem.80.9.7673398. J Clin Endocrinol Metab. 1995. PMID: 7673398 Review. No abstract available.
Constitutively active receptors as a disease-causing mechanism.
Parma J, Duprez L, Van Sande J, Paschke R, Tonacchera M, Dumont J, Vassart G. Parma J, et al. Among authors: tonacchera m. Mol Cell Endocrinol. 1994 Apr;100(1-2):159-62. doi: 10.1016/0303-7207(94)90296-8. Mol Cell Endocrinol. 1994. PMID: 8056151 Review.
Functional characteristics of a variant thyrotropin receptor.
Tonacchera M, Cetani F, Costagliola S, Van Sande J, Refetoff S, Vassart G. Tonacchera M, et al. Eur J Biochem. 1996 Jun 1;238(2):490-4. doi: 10.1111/j.1432-1033.1996.0490z.x. Eur J Biochem. 1996. PMID: 8681963 Free article.
174 results