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Solving the alpha-conotoxin folding problem: efficient selenium-directed on-resin generation of more potent and stable nicotinic acetylcholine receptor antagonists.
Muttenthaler M, Nevin ST, Grishin AA, Ngo ST, Choy PT, Daly NL, Hu SH, Armishaw CJ, Wang CI, Lewis RJ, Martin JL, Noakes PG, Craik DJ, Adams DJ, Alewood PF. Muttenthaler M, et al. Among authors: hu sh. J Am Chem Soc. 2010 Mar 17;132(10):3514-22. doi: 10.1021/ja910602h. J Am Chem Soc. 2010. PMID: 20163143
Combined X-ray and NMR analysis of the stability of the cyclotide cystine knot fold that underpins its insecticidal activity and potential use as a drug scaffold.
Wang CK, Hu SH, Martin JL, Sjögren T, Hajdu J, Bohlin L, Claeson P, Göransson U, Rosengren KJ, Tang J, Tan NH, Craik DJ. Wang CK, et al. Among authors: hu sh. J Biol Chem. 2009 Apr 17;284(16):10672-83. doi: 10.1074/jbc.M900021200. Epub 2009 Feb 10. J Biol Chem. 2009. PMID: 19211551 Free PMC article.
Crystallization and preliminary X-ray diffraction of the Munc18c-syntaxin4 (1-29) complex.
Latham CF, Hu SH, Gee CL, Armishaw CJ, Alewood PF, James DE, Martin JL. Latham CF, et al. Among authors: hu sh. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Jun 1;63(Pt 6):524-8. doi: 10.1107/S1744309107022361. Epub 2007 May 18. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007. PMID: 17554178 Free PMC article.
351 results