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Proteolytic activation of the cell death protease Yama/CPP32 by granzyme B.
Quan LT, Tewari M, O'Rourke K, Dixit V, Snipas SJ, Poirier GG, Ray C, Pickup DJ, Salvesen GS. Quan LT, et al. Among authors: poirier gg. Proc Natl Acad Sci U S A. 1996 Mar 5;93(5):1972-6. doi: 10.1073/pnas.93.5.1972. Proc Natl Acad Sci U S A. 1996. PMID: 8700869 Free PMC article.
Granzyme B/perforin-mediated apoptosis of Jurkat cells results in cleavage of poly(ADP-ribose) polymerase to the 89-kDa apoptotic fragment and less abundant 64-kDa fragment.
Froelich CJ, Hanna WL, Poirier GG, Duriez PJ, D'Amours D, Salvesen GS, Alnemri ES, Earnshaw WC, Shah GM. Froelich CJ, et al. Among authors: poirier gg. Biochem Biophys Res Commun. 1996 Oct 23;227(3):658-65. doi: 10.1006/bbrc.1996.1565. Biochem Biophys Res Commun. 1996. PMID: 8885990
323 results