Claus T - Search Results

1

Differences in beta 3-adrenergic receptor cardiovascular regulation in conscious primates, rats and dogs.

Shen YT, Cervoni P, Claus T, Vatner SF. Shen YT, et al. Among authors: claus t. J Pharmacol Exp Ther. 1996 Sep;278(3):1435-43. J Pharmacol Exp Ther. 1996. PMID: 8819531

2

Specific inhibition of hormone-sensitive lipase improves lipid profile while reducing plasma glucose.

Claus TH, Lowe DB, Liang Y, Salhanick AI, Lubeski CK, Yang L, Lemoine L, Zhu J, Clairmont KB. Claus TH, et al. J Pharmacol Exp Ther. 2005 Dec;315(3):1396-402. doi: 10.1124/jpet.105.086926. Epub 2005 Sep 14. J Pharmacol Exp Ther. 2005. PMID: 16162821

3

Effect of CL-316,243, a thermogenic beta 3-agonist, on energy balance and brown and white adipose tissues in rats.

Himms-Hagen J, Cui J, Danforth E Jr, Taatjes DJ, Lang SS, Waters BL, Claus TH. Himms-Hagen J, et al. Among authors: claus th. Am J Physiol. 1994 Apr;266(4 Pt 2):R1371-82. doi: 10.1152/ajpregu.1994.266.4.R1371. Am J Physiol. 1994. PMID: 7910436

G. Burns, E. E. Largis, J. A. Dolan, and T. H. Claus., J. Med. Chem. 35: 3081, 1992), on energy balance and brown and white adipose tissues (BAT and WAT, respectively) in young rats eating a high-fat diet to induce obesity. ...

G. Burns, E. E. Largis, J. A. Dolan, and T. H. Claus., J. Med. Chem. 35: 3081, 1992), on energy balance and brown and white ad …

4

Hypertrophy of brown adipocytes in brown and white adipose tissues and reversal of diet-induced obesity in rats treated with a beta3-adrenoceptor agonist.

Ghorbani M, Claus TH, Himms-Hagen J. Ghorbani M, et al. Among authors: claus th. Biochem Pharmacol. 1997 Jul 1;54(1):121-31. doi: 10.1016/s0006-2952(97)00162-7. Biochem Pharmacol. 1997. PMID: 9296358

5

Engineering novel VPAC2-selective agonists with improved stability and glucose-lowering activity in vivo.

Pan CQ, Li F, Tom I, Wang W, Dumas M, Froland W, Yung SL, Li Y, Roczniak S, Claus TH, Wang YJ, Whelan JP. Pan CQ, et al. J Pharmacol Exp Ther. 2007 Feb;320(2):900-6. doi: 10.1124/jpet.106.112276. Epub 2006 Nov 16. J Pharmacol Exp Ther. 2007. PMID: 17110523

6

A novel long-acting selective neuropeptide Y2 receptor polyethylene glycol-conjugated peptide agonist reduces food intake and body weight and improves glucose metabolism in rodents.

Ortiz AA, Milardo LF, DeCarr LB, Buckholz TM, Mays MR, Claus TH, Livingston JN, Mahle CD, Lumb KJ. Ortiz AA, et al. J Pharmacol Exp Ther. 2007 Nov;323(2):692-700. doi: 10.1124/jpet.107.125211. Epub 2007 Aug 1. J Pharmacol Exp Ther. 2007. PMID: 17671099

7

A potent and highly selective VPAC2 agonist enhances glucose-induced insulin release and glucose disposal: a potential therapy for type 2 diabetes.

Tsutsumi M, Claus TH, Liang Y, Li Y, Yang L, Zhu J, Dela Cruz F, Peng X, Chen H, Yung SL, Hamren S, Livingston JN, Pan CQ. Tsutsumi M, et al. Diabetes. 2002 May;51(5):1453-60. doi: 10.2337/diabetes.51.5.1453. Diabetes. 2002. PMID: 11978642

8

Design of a long acting peptide functioning as both a glucagon-like peptide-1 receptor agonist and a glucagon receptor antagonist.

Pan CQ, Buxton JM, Yung SL, Tom I, Yang L, Chen H, MacDougall M, Bell A, Claus TH, Clairmont KB, Whelan JP. Pan CQ, et al. J Biol Chem. 2006 May 5;281(18):12506-15. doi: 10.1074/jbc.M600127200. Epub 2006 Feb 27. J Biol Chem. 2006. PMID: 16505481 Free article.

9

Engineering of a VPAC2 receptor peptide agonist to impart dipeptidyl peptidase IV stability and enhance in vivo glucose disposal.

Clairmont KB, Buckholz TM, Pellegrino CM, Buxton JM, Barucci N, Bell A, Ha S, Li F, Claus TH, Salhanick AI, Lumb KJ. Clairmont KB, et al. J Med Chem. 2006 Dec 14;49(25):7545-8. doi: 10.1021/jm0609059. J Med Chem. 2006. PMID: 17149884

10

Dual-acting peptide with prolonged glucagon-like peptide-1 receptor agonist and glucagon receptor antagonist activity for the treatment of type 2 diabetes.

Claus TH, Pan CQ, Buxton JM, Yang L, Reynolds JC, Barucci N, Burns M, Ortiz AA, Roczniak S, Livingston JN, Clairmont KB, Whelan JP. Claus TH, et al. J Endocrinol. 2007 Feb;192(2):371-80. doi: 10.1677/JOE-06-0018. J Endocrinol. 2007. PMID: 17283237

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