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Fatty acid synthase drives the synthesis of phospholipids partitioning into detergent-resistant membrane microdomains.
Swinnen JV, Van Veldhoven PP, Timmermans L, De Schrijver E, Brusselmans K, Vanderhoydonc F, Van de Sande T, Heemers H, Heyns W, Verhoeven G. Swinnen JV, et al. Among authors: van veldhoven pp, van de sande t. Biochem Biophys Res Commun. 2003 Mar 21;302(4):898-903. doi: 10.1016/s0006-291x(03)00265-1. Biochem Biophys Res Commun. 2003. PMID: 12646257
De novo lipogenesis protects cancer cells from free radicals and chemotherapeutics by promoting membrane lipid saturation.
Rysman E, Brusselmans K, Scheys K, Timmermans L, Derua R, Munck S, Van Veldhoven PP, Waltregny D, Daniëls VW, Machiels J, Vanderhoydonc F, Smans K, Waelkens E, Verhoeven G, Swinnen JV. Rysman E, et al. Among authors: van veldhoven pp. Cancer Res. 2010 Oct 15;70(20):8117-26. doi: 10.1158/0008-5472.CAN-09-3871. Epub 2010 Sep 28. Cancer Res. 2010. PMID: 20876798
274 results