Eugui EM - Search Results

1

Structure-activity relationships for inhibition of inosine monophosphate dehydrogenase by nuclear variants of mycophenolic acid.

Nelson PH, Carr SF, Devens BH, Eugui EM, Franco F, Gonzalez C, Hawley RC, Loughhead DG, Milan DJ, Papp E, Patterson JW, Rouhafza S, Sjogren EB, Smith DB, Stephenson RA, Talamas FX, Waltos AM, Weikert RJ, Wu JC. Nelson PH, et al. Among authors: eugui em. J Med Chem. 1996 Oct 11;39(21):4181-96. doi: 10.1021/jm9603633. J Med Chem. 1996. PMID: 8863796

2

Synthesis and immunosuppressive activity of some side-chain variants of mycophenolic acid.

Nelson PH, Eugui E, Wang CC, Allison AC. Nelson PH, et al. J Med Chem. 1990 Feb;33(2):833-8. doi: 10.1021/jm00164a057. J Med Chem. 1990. PMID: 1967654

3

Coordinate inhibition by some antioxidants of TNF alpha, IL-1 beta, and IL-6 production by human peripheral blood mononuclear cells.

Eugui EM, Delustro B, Rouhafza S, Wilhelm R, Allison AC. Eugui EM, et al. Ann N Y Acad Sci. 1993 Nov 30;696:171-84. doi: 10.1111/j.1749-6632.1993.tb17150.x. Ann N Y Acad Sci. 1993. PMID: 8109826 No abstract available.

4

Some antioxidants inhibit, in a co-ordinate fashion, the production of tumor necrosis factor-alpha, IL-beta, and IL-6 by human peripheral blood mononuclear cells.

Eugui EM, DeLustro B, Rouhafza S, Ilnicka M, Lee SW, Wilhelm R, Allison AC. Eugui EM, et al. Int Immunol. 1994 Mar;6(3):409-22. doi: 10.1093/intimm/6.3.409. Int Immunol. 1994. PMID: 8186192

5

Mycophenolic acid, an inhibitor of IMP dehydrogenase that is also an immunosuppressive agent, suppresses the cytokine-induced nitric oxide production in mouse and rat vascular endothelial cells.

Senda M, DeLustro B, Eugui E, Natsumeda Y. Senda M, et al. Transplantation. 1995 Nov 27;60(10):1143-8. doi: 10.1097/00007890-199511270-00015. Transplantation. 1995. PMID: 7482723

6

Mechanisms of action of mycophenolic acid.

Allison AC, Kowalski WJ, Muller CD, Eugui EM. Allison AC, et al. Among authors: eugui em. Ann N Y Acad Sci. 1993 Nov 30;696:63-87. doi: 10.1111/j.1749-6632.1993.tb17143.x. Ann N Y Acad Sci. 1993. PMID: 7906496 Review. No abstract available.

7

Lymphocyte-selective cytostatic and immunosuppressive effects of mycophenolic acid in vitro: role of deoxyguanosine nucleotide depletion.

Eugui EM, Almquist SJ, Muller CD, Allison AC. Eugui EM, et al. Scand J Immunol. 1991 Feb;33(2):161-73. doi: 10.1111/j.1365-3083.1991.tb03746.x. Scand J Immunol. 1991. PMID: 1826793

8

Design and synthesis of orally active inhibitors of TNF synthesis as anti-rheumatoid arthritis drugs.

Chen JJ, Dewdney N, Lin X, Martin RL, Walker KA, Huang J, Chu F, Eugui E, Mirkovich A, Kim Y, Sarma K, Arzeno H, Van Wart HE. Chen JJ, et al. Bioorg Med Chem Lett. 2003 Nov 17;13(22):3951-4. doi: 10.1016/j.bmcl.2003.08.076. Bioorg Med Chem Lett. 2003. PMID: 14592482

9

Mycophenolic acid increases apoptosis, lysosomes and lipid droplets in human lymphoid and monocytic cell lines.

Cohn RG, Mirkovich A, Dunlap B, Burton P, Chiu SH, Eugui E, Caulfield JP. Cohn RG, et al. Transplantation. 1999 Aug 15;68(3):411-8. doi: 10.1097/00007890-199908150-00014. Transplantation. 1999. PMID: 10459546

10

Immunosuppressive and long-acting anti-inflammatory activity of mycophenolic acid and derivative, RS-61443.

Allison AC, Eugui EM. Allison AC, et al. Among authors: eugui em. Br J Rheumatol. 1991;30 Suppl 2:57-61. Br J Rheumatol. 1991. PMID: 1993259 Review. No abstract available.

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