Yu X - Search Results

1

Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1.

Duff K, Eckman C, Zehr C, Yu X, Prada CM, Perez-tur J, Hutton M, Buee L, Harigaya Y, Yager D, Morgan D, Gordon MN, Holcomb L, Refolo L, Zenk B, Hardy J, Younkin S. Duff K, et al. Among authors: yu x. Nature. 1996 Oct 24;383(6602):710-3. doi: 10.1038/383710a0. Nature. 1996. PMID: 8878479

2

Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes.

Holcomb L, Gordon MN, McGowan E, Yu X, Benkovic S, Jantzen P, Wright K, Saad I, Mueller R, Morgan D, Sanders S, Zehr C, O'Campo K, Hardy J, Prada CM, Eckman C, Younkin S, Hsiao K, Duff K. Holcomb L, et al. Among authors: yu x. Nat Med. 1998 Jan;4(1):97-100. doi: 10.1038/nm0198-097. Nat Med. 1998. PMID: 9427614

3

Amyloid phenotype characterization of transgenic mice overexpressing both mutant amyloid precursor protein and mutant presenilin 1 transgenes.

McGowan E, Sanders S, Iwatsubo T, Takeuchi A, Saido T, Zehr C, Yu X, Uljon S, Wang R, Mann D, Dickson D, Duff K. McGowan E, et al. Among authors: yu x. Neurobiol Dis. 1999 Aug;6(4):231-44. doi: 10.1006/nbdi.1999.0243. Neurobiol Dis. 1999. PMID: 10448051

4

Mice transgenic for a human amyloid precursor protein promoter-lacZ reporter construct.

Wright KL, Morgan DG, Yu X, Goss JR, Salbaum JM, Duff K, Gordon MN. Wright KL, et al. Among authors: yu x. J Mol Neurosci. 1999 Aug-Oct;13(1-2):111-20. doi: 10.1385/jmn:13:1-2:111. J Mol Neurosci. 1999. PMID: 10691298

5

Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein.

Lewis J, McGowan E, Rockwood J, Melrose H, Nacharaju P, Van Slegtenhorst M, Gwinn-Hardy K, Paul Murphy M, Baker M, Yu X, Duff K, Hardy J, Corral A, Lin WL, Yen SH, Dickson DW, Davies P, Hutton M. Lewis J, et al. Among authors: yu x. Nat Genet. 2000 Aug;25(4):402-5. doi: 10.1038/78078. Nat Genet. 2000. PMID: 10932182

6

A loss of function mutation of presenilin-2 interferes with amyloid beta-peptide production and notch signaling.

Steiner H, Duff K, Capell A, Romig H, Grim MG, Lincoln S, Hardy J, Yu X, Picciano M, Fechteler K, Citron M, Kopan R, Pesold B, Keck S, Baader M, Tomita T, Iwatsubo T, Baumeister R, Haass C. Steiner H, et al. Among authors: yu x. J Biol Chem. 1999 Oct 1;274(40):28669-73. doi: 10.1074/jbc.274.40.28669. J Biol Chem. 1999. PMID: 10497236 Free article.

7

Functional phenotype in transgenic mice expressing mutant human presenilin-1.

Barrow PA, Empson RM, Gladwell SJ, Anderson CM, Killick R, Yu X, Jefferys JG, Duff K. Barrow PA, et al. Among authors: yu x. Neurobiol Dis. 2000 Apr;7(2):119-26. doi: 10.1006/nbdi.1999.0276. Neurobiol Dis. 2000. PMID: 10783295

8

Characterization of pathology in transgenic mice over-expressing human genomic and cDNA tau transgenes.

Duff K, Knight H, Refolo LM, Sanders S, Yu X, Picciano M, Malester B, Hutton M, Adamson J, Goedert M, Burki K, Davies P. Duff K, et al. Among authors: yu x. Neurobiol Dis. 2000 Apr;7(2):87-98. doi: 10.1006/nbdi.1999.0279. Neurobiol Dis. 2000. PMID: 10783293

9

Lack of nigral pathology in transgenic mice expressing human alpha-synuclein driven by the tyrosine hydroxylase promoter.

Matsuoka Y, Vila M, Lincoln S, McCormack A, Picciano M, LaFrancois J, Yu X, Dickson D, Langston WJ, McGowan E, Farrer M, Hardy J, Duff K, Przedborski S, Di Monte DA. Matsuoka Y, et al. Among authors: yu x. Neurobiol Dis. 2001 Jun;8(3):535-9. doi: 10.1006/nbdi.2001.0392. Neurobiol Dis. 2001. PMID: 11442360

10

Wild-type human TDP-43 expression causes TDP-43 phosphorylation, mitochondrial aggregation, motor deficits, and early mortality in transgenic mice.

Xu YF, Gendron TF, Zhang YJ, Lin WL, D'Alton S, Sheng H, Casey MC, Tong J, Knight J, Yu X, Rademakers R, Boylan K, Hutton M, McGowan E, Dickson DW, Lewis J, Petrucelli L. Xu YF, et al. Among authors: yu x. J Neurosci. 2010 Aug 11;30(32):10851-9. doi: 10.1523/JNEUROSCI.1630-10.2010. J Neurosci. 2010. PMID: 20702714 Free PMC article.

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