Georgopoulos S - Search Results

1

Transgenic and knockout analyses of the role of TNF in immune regulation and disease pathogenesis.

Douni E, Akassoglou K, Alexopoulou L, Georgopoulos S, Haralambous S, Hill S, Kassiotis G, Kontoyiannis D, Pasparakis M, Plows D, Probert L, Kollias G. Douni E, et al. Among authors: georgopoulos s. J Inflamm. 1995-1996;47(1-2):27-38. J Inflamm. 1995. PMID: 8913927 Review.

2

Transmembrane TNF is sufficient to induce localized tissue toxicity and chronic inflammatory arthritis in transgenic mice.

Georgopoulos S, Plows D, Kollias G. Georgopoulos S, et al. J Inflamm. 1996;46(2):86-97. J Inflamm. 1996. PMID: 8734789

3

Transgenic mice expressing human tumour necrosis factor: a predictive genetic model of arthritis.

Keffer J, Probert L, Cazlaris H, Georgopoulos S, Kaslaris E, Kioussis D, Kollias G. Keffer J, et al. Among authors: georgopoulos s. EMBO J. 1991 Dec;10(13):4025-31. doi: 10.1002/j.1460-2075.1991.tb04978.x. EMBO J. 1991. PMID: 1721867 Free PMC article.

4

The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor.

Grell M, Douni E, Wajant H, Löhden M, Clauss M, Maxeiner B, Georgopoulos S, Lesslauer W, Kollias G, Pfizenmaier K, Scheurich P. Grell M, et al. Among authors: georgopoulos s. Cell. 1995 Dec 1;83(5):793-802. doi: 10.1016/0092-8674(95)90192-2. Cell. 1995. PMID: 8521496 Free article.

5

Peripheral Tumor Necrosis Factor-Alpha (TNF-α) Modulates Amyloid Pathology by Regulating Blood-Derived Immune Cells and Glial Response in the Brain of AD/TNF Transgenic Mice.

Paouri E, Tzara O, Kartalou GI, Zenelak S, Georgopoulos S. Paouri E, et al. Among authors: georgopoulos s. J Neurosci. 2017 May 17;37(20):5155-5171. doi: 10.1523/JNEUROSCI.2484-16.2017. Epub 2017 Apr 25. J Neurosci. 2017. PMID: 28442538 Free PMC article.

6

A 3'UTR modification of the TNF-α mouse gene increases peripheral TNF-α and modulates the Alzheimer-like phenotype in 5XFAD mice.

Kalovyrna N, Apokotou O, Boulekou S, Paouri E, Boutou A, Georgopoulos S. Kalovyrna N, et al. Among authors: georgopoulos s. Sci Rep. 2020 May 26;10(1):8670. doi: 10.1038/s41598-020-65378-2. Sci Rep. 2020. PMID: 32457323 Free PMC article.

7

Genetic Deletion of Tumor Necrosis Factor-α Attenuates Amyloid-β Production and Decreases Amyloid Plaque Formation and Glial Response in the 5XFAD Model of Alzheimer's Disease.

Paouri E, Tzara O, Zenelak S, Georgopoulos S. Paouri E, et al. Among authors: georgopoulos s. J Alzheimers Dis. 2017;60(1):165-181. doi: 10.3233/JAD-170065. J Alzheimers Dis. 2017. PMID: 28826177

8

Generation and characterization of two transgenic mouse lines expressing human ApoE2 in neurons and glial cells.

Georgopoulos S, McKee A, Kan HY, Zannis VI. Georgopoulos S, et al. Biochemistry. 2002 Jul 30;41(30):9293-301. doi: 10.1021/bi015971l. Biochemistry. 2002. PMID: 12135350

9

The SP1 sites of the human apoCIII enhancer are essential for the expression of the apoCIII gene and contribute to the hepatic and intestinal expression of the apoA-I gene in transgenic mice.

Georgopoulos S, Kan HY, Reardon-Alulis C, Zannis V. Georgopoulos S, et al. Nucleic Acids Res. 2000 Dec 15;28(24):4919-29. doi: 10.1093/nar/28.24.4919. Nucleic Acids Res. 2000. PMID: 11121483 Free PMC article.

10

Systemic and CNS Inflammation Crosstalk: Implications for Alzheimer's Disease.

Paouri E, Georgopoulos S. Paouri E, et al. Among authors: georgopoulos s. Curr Alzheimer Res. 2019;16(6):559-574. doi: 10.2174/1567205016666190321154618. Curr Alzheimer Res. 2019. PMID: 30907316 Review.

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