Targeted disruption of the ABP-120 gene leads to cells with altered motility.
Cox D, Condeelis J, Wessels D, Soll D, Kern H, Knecht DA.
Cox D, et al. Among authors: condeelis j.
J Cell Biol. 1992 Feb;116(4):943-55. doi: 10.1083/jcb.116.4.943.
J Cell Biol. 1992.
PMID: 1310321
Free PMC article.
This phenotype is consistent with a role for ABP-120 in pseudopod extension by cross-linking actin filaments as proposed by the "cortical expansion model" (Condeelis, J., A. Bresnick, M. Demma, C. Dharmawardhane, R. Eddy, A. L. Hall, R. Sauterer, and V. ...
This phenotype is consistent with a role for ABP-120 in pseudopod extension by cross-linking actin filaments as proposed by the "cortical ex …