Klumb LA - Search Results

1

Antibody fragments in tumor pretargeting. Evaluation of biotinylated Fab' colocalization with recombinant streptavidin and avidin.

Wilbur DS, Hamlin DK, Vessella RL, Stray JE, Buhler KR, Stayton PS, Klumb LA, Pathare PM, Weerawarna SA. Wilbur DS, et al. Among authors: klumb la. Bioconjug Chem. 1996 Nov-Dec;7(6):689-702. doi: 10.1021/bc9600628. Bioconjug Chem. 1996. PMID: 8950488

2

Streptavidin in antibody pretargeting. Comparison of a recombinant streptavidin with two streptavidin mutant proteins and two commercially available streptavidin proteins.

Wilbur DS, Stayton PS, To R, Buhler KR, Klumb LA, Hamlin DK, Stray JE, Vessella RL. Wilbur DS, et al. Among authors: klumb la. Bioconjug Chem. 1998 Jan-Feb;9(1):100-7. doi: 10.1021/bc970152s. Bioconjug Chem. 1998. PMID: 9460552

3

Development of new biotin/streptavidin reagents for pretargeting.

Wilbur DS, Pathare PM, Hamlin DK, Stayton PS, To R, Klumb LA, Buhler KR, Vessella RL. Wilbur DS, et al. Among authors: klumb la. Biomol Eng. 1999 Dec 31;16(1-4):113-8. doi: 10.1016/s1050-3862(99)00044-3. Biomol Eng. 1999. PMID: 10796993 Review.

4

Structural studies of the streptavidin binding loop.

Freitag S, Le Trong I, Klumb L, Stayton PS, Stenkamp RE. Freitag S, et al. Protein Sci. 1997 Jun;6(6):1157-66. doi: 10.1002/pro.5560060604. Protein Sci. 1997. PMID: 9194176 Free PMC article.

5

Energetic roles of hydrogen bonds at the ureido oxygen binding pocket in the streptavidin-biotin complex.

Klumb LA, Chu V, Stayton PS. Klumb LA, et al. Biochemistry. 1998 May 26;37(21):7657-63. doi: 10.1021/bi9803123. Biochemistry. 1998. PMID: 9601024

6

Structural studies of binding site tryptophan mutants in the high-affinity streptavidin-biotin complex.

Freitag S, Le Trong I, Chilkoti A, Klumb LA, Stayton PS, Stenkamp RE. Freitag S, et al. Among authors: klumb la. J Mol Biol. 1998 May 29;279(1):211-21. doi: 10.1006/jmbi.1998.1735. J Mol Biol. 1998. PMID: 9636711

7

Atomic resolution structure of biotin-free Tyr43Phe streptavidin: what is in the binding site?

Freitag S, Le Trong I, Klumb LA, Stayton PS, Stenkamp RE. Freitag S, et al. Among authors: klumb la. Acta Crystallogr D Biol Crystallogr. 1999 Jun;55(Pt 6):1118-26. doi: 10.1107/s0907444999002322. Acta Crystallogr D Biol Crystallogr. 1999. PMID: 10329773

8

A structural snapshot of an intermediate on the streptavidin-biotin dissociation pathway.

Freitag S, Chu V, Penzotti JE, Klumb LA, To R, Hyre D, Le Trong I, Lybrand TP, Stenkamp RE, Stayton PS. Freitag S, et al. Among authors: klumb la. Proc Natl Acad Sci U S A. 1999 Jul 20;96(15):8384-9. doi: 10.1073/pnas.96.15.8384. Proc Natl Acad Sci U S A. 1999. PMID: 10411884 Free PMC article.

9

X-ray crystallographic studies of streptavidin mutants binding to biotin.

Freitag S, Le Trong I, Klumb LA, Chu V, Chilkoti A, Stayton PS, Stenkamp RE. Freitag S, et al. Among authors: klumb la. Biomol Eng. 1999 Dec 31;16(1-4):13-9. doi: 10.1016/s1050-3862(99)00048-0. Biomol Eng. 1999. PMID: 10796980

10

Streptavidin-biotin binding energetics.

Stayton PS, Freitag S, Klumb LA, Chilkoti A, Chu V, Penzotti JE, To R, Hyre D, Le Trong I, Lybrand TP, Stenkamp RE. Stayton PS, et al. Among authors: klumb la. Biomol Eng. 1999 Dec 31;16(1-4):39-44. doi: 10.1016/s1050-3862(99)00042-x. Biomol Eng. 1999. PMID: 10796983 Review.

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