Sepp-Lorenzino L - Search Results

1

Targeted therapy for prostate cancer: the Memorial Sloan-Kettering Cancer Center approach.

Slovin SF, Livingston PO, Rosen N, Sepp-Lorenzino L, Kelly WK, Mendelsohn J, Scher HI. Slovin SF, et al. Semin Oncol. 1996 Dec;23(6 Suppl 14):41-8. Semin Oncol. 1996. PMID: 8996585 Review.

2

A peptidomimetic inhibitor of ras functionality markedly suppresses growth of human prostate tumor xenografts in mice. Prospects for long-term clinical utility.

Sirotnak FM, Sepp-Lorenzino L, Kohl NE, Rosen N, Scher HI. Sirotnak FM, et al. Cancer Chemother Pharmacol. 2000;46(1):79-83. doi: 10.1007/s002800000126. Cancer Chemother Pharmacol. 2000. PMID: 10912583

3

Insulin and insulin-like growth factor signaling are defective in the MDA MB-468 human breast cancer cell line.

Sepp-Lorenzino L, Rosen N, Lebwohl DE. Sepp-Lorenzino L, et al. Cell Growth Differ. 1994 Oct;5(10):1077-83. Cell Growth Differ. 1994. PMID: 7848909

4

ras Mutation: does it have clinical import?

Rosen N, Sepp-Lorenzino L. Rosen N, et al. Cancer J Sci Am. 1997 Sep-Oct;3(5):271-2. Cancer J Sci Am. 1997. PMID: 9327149 Review. No abstract available.

5

A farnesyl-protein transferase inhibitor induces p21 expression and G1 block in p53 wild type tumor cells.

Sepp-Lorenzino L, Rosen N. Sepp-Lorenzino L, et al. J Biol Chem. 1998 Aug 7;273(32):20243-51. doi: 10.1074/jbc.273.32.20243. J Biol Chem. 1998. PMID: 9685373 Free article.

6

Synthesis and evaluation of geldanamycin-testosterone hybrids.

Kuduk SD, Harris TC, Zheng FF, Sepp-Lorenzino L, Ouerfelli Q, Rosen N, Danishefsky SJ. Kuduk SD, et al. Bioorg Med Chem Lett. 2000 Jun 5;10(11):1303-6. doi: 10.1016/s0960-894x(00)00208-0. Bioorg Med Chem Lett. 2000. PMID: 10866406

7

Farnesyl:protein transferase inhibitors as potential agents for the management of human prostate cancer.

Sepp-Lorenzino L, Tjaden G, Moasser MM, Timaul N, Ma Z, Kohl NE, Gibbs JB, Oliff A, Rosen N, Scher HI. Sepp-Lorenzino L, et al. Prostate Cancer Prostatic Dis. 2001;4(1):33-43. doi: 10.1038/sj.pcan.4500491. Prostate Cancer Prostatic Dis. 2001. PMID: 12497061

8

A peptidomimetic inhibitor of farnesyl:protein transferase blocks the anchorage-dependent and -independent growth of human tumor cell lines.

Sepp-Lorenzino L, Ma Z, Rands E, Kohl NE, Gibbs JB, Oliff A, Rosen N. Sepp-Lorenzino L, et al. Cancer Res. 1995 Nov 15;55(22):5302-9. Cancer Res. 1995. PMID: 7585592

9

Signal transduction pathways induced by heregulin in MDA-MB-453 breast cancer cells.

Sepp-Lorenzino L, Eberhard I, Ma Z, Cho C, Serve H, Liu F, Rosen N, Lupu R. Sepp-Lorenzino L, et al. Oncogene. 1996 Apr 18;12(8):1679-87. Oncogene. 1996. PMID: 8622888

10

Pharmacologic shifting of a balance between protein refolding and degradation mediated by Hsp90.

Schneider C, Sepp-Lorenzino L, Nimmesgern E, Ouerfelli O, Danishefsky S, Rosen N, Hartl FU. Schneider C, et al. Proc Natl Acad Sci U S A. 1996 Dec 10;93(25):14536-41. doi: 10.1073/pnas.93.25.14536. Proc Natl Acad Sci U S A. 1996. PMID: 8962087 Free PMC article.

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