Spence S - Search Results

1

Receptor-mediated stimulation of lipid signalling pathways in CHO cells elicits the rapid transient induction of the PDE1B isoform of Ca2+/calmodulin-stimulated cAMP phosphodiesterase.

Spence S, Rena G, Sullivan M, Erdogan S, Houslay MD. Spence S, et al. Biochem J. 1997 Jan 1;321 ( Pt 1)(Pt 1):157-63. doi: 10.1042/bj3210157. Biochem J. 1997. PMID: 9003415 Free PMC article.

2

The local anaesthetic benzyl alcohol attenuates the alpha 2-adrenoceptor-mediated inhibition of human platelet adenylate cyclase activity when stimulated by prostaglandin E1, but not that stimulated by forskolin.

Spence S, Houslay MD. Spence S, et al. Biochem J. 1989 Dec 1;264(2):483-8. doi: 10.1042/bj2640483. Biochem J. 1989. PMID: 2557841 Free PMC article.

3

Induction of Ca2+/calmodulin-stimulated cyclic AMP phosphodiesterase (PDE1) activity in Chinese hamster ovary cells (CHO) by phorbol 12-myristate 13-acetate and by the selective overexpression of protein kinase C isoforms.

Spence S, Rena G, Sweeney G, Houslay MD. Spence S, et al. Biochem J. 1995 Sep 15;310 ( Pt 3)(Pt 3):975-82. doi: 10.1042/bj3100975. Biochem J. 1995. PMID: 7575435 Free PMC article.

4

Alternative splicing of the type-IVA cyclic AMP phosphodiesterase gene provides isoform variants with distinct N-terminal domains fused to a common, soluble catalytic unit: 'designer' changes in Vmax, stability and membrane association.

Houslay MD, Scotland G, Pooley L, Spence S, Wilkinson I, McCallum F, Julien P, Rena NG, Michie AM, Erdogan S, et al. Houslay MD, et al. Among authors: spence s. Biochem Soc Trans. 1995 May;23(2):393-8. doi: 10.1042/bst0230393. Biochem Soc Trans. 1995. PMID: 7672427 Review. No abstract available.

5

The role of Gi and the membrane-fluidizing agent benzyl alcohol in modulating the hysteretic activation of human platelet adenylate cyclase by guanylyl 5'-imidodiphosphate.

Spence S, Houslay MD. Spence S, et al. Biochem J. 1993 May 1;291 ( Pt 3)(Pt 3):945-9. doi: 10.1042/bj2910945. Biochem J. 1993. PMID: 8489520 Free PMC article.

6

Guanine nucleotide regulatory proteins in insulin's action and in diabetes.

Houslay MD, Pyne NJ, O'Brien RM, Siddle K, Strassheim D, Palmer T, Spence S, Woods M, Wilson A, Lavan B, et al. Houslay MD, et al. Among authors: spence s. Biochem Soc Trans. 1989 Aug;17(4):627-9. doi: 10.1042/bst0170627. Biochem Soc Trans. 1989. PMID: 2504628 Review. No abstract available.

7

Dietary linoleic acid-induced changes in respiratory beta-adrenergic receptor function and the form of arrhenius plots of isoprenaline- and prostaglandin E2-stimulated adenylate cyclase activity in a model for atopy.

Loesberg C, Spence S, Nijkamp FP, Houslay MD. Loesberg C, et al. Among authors: spence s. Cell Signal. 1994 Feb;6(2):187-99. doi: 10.1016/0898-6568(94)90076-0. Cell Signal. 1994. PMID: 8086282

8

Spatial and temporal dissociation in prefrontal cortex during action execution.

Hunter MD, Green RD, Wilkinson ID, Spence SA. Hunter MD, et al. Neuroimage. 2004 Nov;23(3):1186-91. doi: 10.1016/j.neuroimage.2004.07.047. Neuroimage. 2004. PMID: 15528118 Clinical Trial.

9

Modafinil modulates anterior cingulate function in chronic schizophrenia.

Spence SA, Green RD, Wilkinson ID, Hunter MD. Spence SA, et al. Br J Psychiatry. 2005 Jul;187:55-61. doi: 10.1192/bjp.187.1.55. Br J Psychiatry. 2005. PMID: 15994572 Clinical Trial.

10

Impact of modafinil on prefrontal executive function in schizophrenia.

Hunter MD, Ganesan V, Wilkinson ID, Spence SA. Hunter MD, et al. Am J Psychiatry. 2006 Dec;163(12):2184-6. doi: 10.1176/appi.ajp.163.12.2184. Am J Psychiatry. 2006. PMID: 17151173 Clinical Trial.

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