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Obese gene expression: reduction by fasting and stimulation by insulin and glucose in lean mice, and persistent elevation in acquired (diet-induced) and genetic (yellow agouti) obesity.
Mizuno TM, Bergen H, Funabashi T, Kleopoulos SP, Zhong YG, Bauman WA, Mobbs CV. Mizuno TM, et al. Among authors: kleopoulos sp. Proc Natl Acad Sci U S A. 1996 Apr 16;93(8):3434-8. doi: 10.1073/pnas.93.8.3434. Proc Natl Acad Sci U S A. 1996. PMID: 8622953 Free PMC article.
Hypothalamic Fkbp51 is induced by fasting, and elevated hypothalamic expression promotes obese phenotypes.
Yang L, Isoda F, Yen K, Kleopoulos SP, Janssen W, Fan X, Mastaitis J, Dunn-Meynell A, Levin B, McCrimmon R, Sherwin R, Musatov S, Mobbs CV. Yang L, et al. Among authors: kleopoulos sp. Am J Physiol Endocrinol Metab. 2012 Apr 15;302(8):E987-91. doi: 10.1152/ajpendo.00474.2011. Epub 2012 Feb 7. Am J Physiol Endocrinol Metab. 2012. PMID: 22318949 Free PMC article.
43 results