Smith CP - Search Results

1

Pharmacological activity and safety profile of P10358, a novel, orally active acetylcholinesterase inhibitor for Alzheimer's disease.

Smith CP, Bores GM, Petko W, Li M, Selk DE, Rush DK, Camacho F, Winslow JT, Fishkin R, Cunningham DM, Brooks KM, Roehr J, Hartman HB, Davis L, Vargas HM. Smith CP, et al. J Pharmacol Exp Ther. 1997 Feb;280(2):710-20. J Pharmacol Exp Ther. 1997. PMID: 9023283

2

alpha-Adrenergic activity and cardiovascular effects of besipirdine HCl (HP 749) and metabolite P7480 in vitro and in the conscious rat and dog.

Hubbard JW, Nordstrom ST, Smith CP, Brooks KM, Laws-Ricker L, Zhou L, Vargas HM. Hubbard JW, et al. Among authors: smith cp. J Pharmacol Exp Ther. 1997 Apr;281(1):337-46. J Pharmacol Exp Ther. 1997. PMID: 9103515

3

Alpha 2-adrenoceptor antagonists potentiate acetylcholinesterase inhibitor effects on passive avoidance learning in the rat.

Camacho F, Smith CP, Vargas HM, Winslow JT. Camacho F, et al. Among authors: smith cp. Psychopharmacology (Berl). 1996 Apr;124(4):347-54. doi: 10.1007/BF02247440. Psychopharmacology (Berl). 1996. PMID: 8739550

4

Aminopyridine carbamic acid esters: synthesis and potential as acetylcholinesterase inhibitors and acetylcholine releasers.

Shutske GM, Tomer JD, Kapples KJ, Hrib NJ, Jurcak JG, Bores GM, Huger FP, Petko W, Smith CP. Shutske GM, et al. Among authors: smith cp. J Pharm Sci. 1992 Apr;81(4):380-5. doi: 10.1002/jps.2600810419. J Pharm Sci. 1992. PMID: 1501077

5

Synthesis and structure-activity relationships of N-propyl-N-(4-pyridinyl)-1H-indol-1-amine (besipirdine) and related analogs as potential therapeutic agents for Alzheimer's disease.

Klein JT, Davis L, Olsen GE, Wong GS, Huger FP, Smith CP, Petko WW, Cornfeldt M, Wilker JC, Blitzer RD, Landau E, Haroutunian V, Martin LL, Effland RC. Klein JT, et al. Among authors: smith cp. J Med Chem. 1996 Jan 19;39(2):570-81. doi: 10.1021/jm9506433. J Med Chem. 1996. PMID: 8558529

6

Substituted (pyrroloamino)pyridines: potential agents for the treatment of Alzheimer's disease.

Davis L, Olsen GE, Klein JT, Kapples KJ, Huger FP, Smith CP, Petko WW, Cornfeldt M, Effland RC. Davis L, et al. Among authors: smith cp. J Med Chem. 1996 Jan 19;39(2):582-7. doi: 10.1021/jm950644v. J Med Chem. 1996. PMID: 8558530

7

Serotonergic activity of HP 184: does spontaneous release have a role?

Smith CP, Woods-Kettelberger AT, Corbett R, Chesson SM, Bores GM, Petko WW, Roehr JE, Kongsamut S. Smith CP, et al. Neurochem Res. 1996 May;21(5):575-83. doi: 10.1007/BF02527756. Neurochem Res. 1996. PMID: 8726966

8

HP 749 enhances calcium-independent release of [3H]norepinephrine from rat cortical slices and synaptosomes.

Smith CP, Huger FP, Petko W, Kongsamut S. Smith CP, et al. Neurochem Res. 1994 Oct;19(10):1265-70. doi: 10.1007/BF01006816. Neurochem Res. 1994. PMID: 7891842

9

Beta-amyloid1-40 inhibits electrically stimulated release of [3H]norepinephrine and enhances the internal calcium response to low potassium in rat cortex: prevention with a free radical scavenger.

Li M, Smith CP. Li M, et al. Among authors: smith cp. Brain Res Bull. 1996;39(5):299-303. doi: 10.1016/0361-9230(96)00031-7. Brain Res Bull. 1996. PMID: 8705317

10

Besipirdine (HP 749) reduces schedule-induced polydipsia in rats.

Woods-Kettelberger AT, Smith CP, Corbett R, Szewczak MR, Roehr JE, Bores GM, Klein JT, Kongsamut S. Woods-Kettelberger AT, et al. Among authors: smith cp. Brain Res Bull. 1996;41(2):125-30. Brain Res Bull. 1996. PMID: 8879677

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