Chien KR - Search Results

1

MLP-deficient mice exhibit a disruption of cardiac cytoarchitectural organization, dilated cardiomyopathy, and heart failure.

Arber S, Hunter JJ, Ross J Jr, Hongo M, Sansig G, Borg J, Perriard JC, Chien KR, Caroni P. Arber S, et al. Among authors: chien kr. Cell. 1997 Feb 7;88(3):393-403. doi: 10.1016/s0092-8674(00)81878-4. Cell. 1997. PMID: 9039266 Free article.

2

Point mutations in human beta cardiac myosin heavy chain have differential effects on sarcomeric structure and assembly: an ATP binding site change disrupts both thick and thin filaments, whereas hypertrophic cardiomyopathy mutations display normal assembly.

Becker KD, Gottshall KR, Hickey R, Perriard JC, Chien KR. Becker KD, et al. Among authors: chien kr. J Cell Biol. 1997 Apr 7;137(1):131-40. doi: 10.1083/jcb.137.1.131. J Cell Biol. 1997. PMID: 9105042 Free PMC article.

3

Effects of growth hormone on cardiac dysfunction and gene expression in genetic murine dilated cardiomyopathy.

Hongo M, Ryoke T, Schoenfeld J, Hunter J, Dalton N, Clark R, Lowe D, Chien K, Ross J Jr. Hongo M, et al. Basic Res Cardiol. 2000 Dec;95(6):431-41. doi: 10.1007/s003950070018. Basic Res Cardiol. 2000. PMID: 11192363

4

Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress.

Hirota H, Chen J, Betz UA, Rajewsky K, Gu Y, Ross J Jr, Müller W, Chien KR. Hirota H, et al. Among authors: chien kr. Cell. 1999 Apr 16;97(2):189-98. doi: 10.1016/s0092-8674(00)80729-1. Cell. 1999. PMID: 10219240 Free article.

5

Signaling pathways for cardiac hypertrophy and failure.

Hunter JJ, Chien KR. Hunter JJ, et al. Among authors: chien kr. N Engl J Med. 1999 Oct 21;341(17):1276-83. doi: 10.1056/NEJM199910213411706. N Engl J Med. 1999. PMID: 10528039 Review. No abstract available.

6

Chronic phospholamban-sarcoplasmic reticulum calcium ATPase interaction is the critical calcium cycling defect in dilated cardiomyopathy.

Minamisawa S, Hoshijima M, Chu G, Ward CA, Frank K, Gu Y, Martone ME, Wang Y, Ross J Jr, Kranias EG, Giles WR, Chien KR. Minamisawa S, et al. Among authors: chien kr. Cell. 1999 Oct 29;99(3):313-22. doi: 10.1016/s0092-8674(00)81662-1. Cell. 1999. PMID: 10555147 Free article.

7

Ventricular expression of a MLC-2v-ras fusion gene induces cardiac hypertrophy and selective diastolic dysfunction in transgenic mice.

Hunter JJ, Tanaka N, Rockman HA, Ross J Jr, Chien KR. Hunter JJ, et al. Among authors: chien kr. J Biol Chem. 1995 Sep 29;270(39):23173-8. doi: 10.1074/jbc.270.39.23173. J Biol Chem. 1995. PMID: 7559464 Free article.

8

A genetic based model of cardiac hypertrophy in MLC-ras mice.

Gottshall KR, Becker KD, Hunter JJ, Chien KR. Gottshall KR, et al. Among authors: chien kr. J Card Fail. 1996 Dec;2(4 Suppl):S28-34. J Card Fail. 1996. PMID: 8951558 Review. No abstract available.

9

Effects of deletion of muscle LIM protein on myocyte function.

Su Z, Yao A, Zubair I, Sugishita K, Ritter M, Li F, Hunter JJ, Chien KR, Barry WH. Su Z, et al. Among authors: chien kr. Am J Physiol Heart Circ Physiol. 2001 Jun;280(6):H2665-73. doi: 10.1152/ajpheart.2001.280.6.H2665. Am J Physiol Heart Circ Physiol. 2001. PMID: 11356623 Free article.

10

Ras-dependent pathways induce obstructive hypertrophy in echo-selected transgenic mice.

Gottshall KR, Hunter JJ, Tanaka N, Dalton N, Becker KD, Ross J Jr, Chien KR. Gottshall KR, et al. Among authors: chien kr. Proc Natl Acad Sci U S A. 1997 Apr 29;94(9):4710-5. doi: 10.1073/pnas.94.9.4710. Proc Natl Acad Sci U S A. 1997. PMID: 9114056 Free PMC article.

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