High K - Search Results

1

Recombinant adeno-associated virus for muscle directed gene therapy.

Fisher KJ, Jooss K, Alston J, Yang Y, Haecker SE, High K, Pathak R, Raper SE, Wilson JM. Fisher KJ, et al. Among authors: high k. Nat Med. 1997 Mar;3(3):306-12. doi: 10.1038/nm0397-306. Nat Med. 1997. PMID: 9055858

2

Stable gene transfer and expression of human blood coagulation factor IX after intramuscular injection of recombinant adeno-associated virus.

Herzog RW, Hagstrom JN, Kung SH, Tai SJ, Wilson JM, Fisher KJ, High KA. Herzog RW, et al. Among authors: high ka. Proc Natl Acad Sci U S A. 1997 May 27;94(11):5804-9. doi: 10.1073/pnas.94.11.5804. Proc Natl Acad Sci U S A. 1997. PMID: 9159155 Free PMC article.

3

CD8(+) T-cell responses to adeno-associated virus capsid in humans.

Mingozzi F, Maus MV, Hui DJ, Sabatino DE, Murphy SL, Rasko JE, Ragni MV, Manno CS, Sommer J, Jiang H, Pierce GF, Ertl HC, High KA. Mingozzi F, et al. Nat Med. 2007 Apr;13(4):419-22. doi: 10.1038/nm1549. Epub 2007 Mar 18. Nat Med. 2007. PMID: 17369837

4

Long-term correction of canine hemophilia B by gene transfer of blood coagulation factor IX mediated by adeno-associated viral vector.

Herzog RW, Yang EY, Couto LB, Hagstrom JN, Elwell D, Fields PA, Burton M, Bellinger DA, Read MS, Brinkhous KM, Podsakoff GM, Nichols TC, Kurtzman GJ, High KA. Herzog RW, et al. Among authors: high ka. Nat Med. 1999 Jan;5(1):56-63. doi: 10.1038/4743. Nat Med. 1999. PMID: 9883840

5

Adeno-associated viral vector-mediated gene transfer of human blood coagulation factor IX into mouse liver.

Nakai H, Herzog RW, Hagstrom JN, Walter J, Kung SH, Yang EY, Tai SJ, Iwaki Y, Kurtzman GJ, Fisher KJ, Colosi P, Couto LB, High KA. Nakai H, et al. Among authors: high ka. Blood. 1998 Jun 15;91(12):4600-7. Blood. 1998. PMID: 9616156 Free article.

6

Cardiac gene transfer of short hairpin RNA directed against phospholamban effectively knocks down gene expression but causes cellular toxicity in canines.

Bish LT, Sleeper MM, Reynolds C, Gazzara J, Withnall E, Singletary GE, Buchlis G, Hui D, High KA, Gao G, Wilson JM, Sweeney HL. Bish LT, et al. Hum Gene Ther. 2011 Aug;22(8):969-77. doi: 10.1089/hum.2011.035. Epub 2011 Jun 8. Hum Gene Ther. 2011. PMID: 21542669 Free PMC article.

7

Progress and prospects: gene therapy clinical trials (part 2).

Aiuti A, Bachoud-Lévi AC, Blesch A, Brenner MK, Cattaneo F, Chiocca EA, Gao G, High KA, Leen AM, Lemoine NR, McNeish IA, Meneguzzi G, Peschanski M, Roncarolo MG, Strayer DS, Tuszynski MH, Waxman DJ, Wilson JM. Aiuti A, et al. Among authors: high ka. Gene Ther. 2007 Nov;14(22):1555-63. doi: 10.1038/sj.gt.3303033. Gene Ther. 2007. PMID: 17984995 Review.

8

Improved hepatic gene transfer by using an adeno-associated virus serotype 5 vector.

Mingozzi F, Schüttrumpf J, Arruda VR, Liu Y, Liu YL, High KA, Xiao W, Herzog RW. Mingozzi F, et al. J Virol. 2002 Oct;76(20):10497-502. doi: 10.1128/jvi.76.20.10497-10502.2002. J Virol. 2002. PMID: 12239326 Free PMC article.

9

Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response.

Manno CS, Pierce GF, Arruda VR, Glader B, Ragni M, Rasko JJ, Ozelo MC, Hoots K, Blatt P, Konkle B, Dake M, Kaye R, Razavi M, Zajko A, Zehnder J, Rustagi PK, Nakai H, Chew A, Leonard D, Wright JF, Lessard RR, Sommer JM, Tigges M, Sabatino D, Luk A, Jiang H, Mingozzi F, Couto L, Ertl HC, High KA, Kay MA. Manno CS, et al. Among authors: high ka. Nat Med. 2006 Mar;12(3):342-7. doi: 10.1038/nm1358. Epub 2006 Feb 12. Nat Med. 2006. PMID: 16474400 Clinical Trial.

10

Influence of vector dose on factor IX-specific T and B cell responses in muscle-directed gene therapy.

Herzog RW, Fields PA, Arruda VR, Brubaker JO, Armstrong E, McClintock D, Bellinger DA, Couto LB, Nichols TC, High KA. Herzog RW, et al. Hum Gene Ther. 2002 Jul 20;13(11):1281-91. doi: 10.1089/104303402760128513. Hum Gene Ther. 2002. PMID: 12162811

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