Woodward RM - Search Results

1

Structure-activity relationships of alkyl- and alkoxy-substituted 1,4-dihydroquinoxaline-2,3-diones: potent and systemically active antagonists for the glycine site of the NMDA receptor.

Cai SX, Kher SM, Zhou ZL, Ilyin V, Espitia SA, Tran M, Hawkinson JE, Woodward RM, Weber E, Keana JF. Cai SX, et al. Among authors: woodward rm. J Med Chem. 1997 Feb 28;40(5):730-8. doi: 10.1021/jm960654b. J Med Chem. 1997. PMID: 9057859

2

Synthesis and SAR of novel di- and trisubstituted 1,4-dihydroquinoxaline-2,3-diones related to licostinel (Acea 1021) as NMDA/glycine site antagonists.

Zhou ZL, Kher SM, Cai SX, Whittemore ER, Espitia SA, Hawkinson JE, Tran M, Woodward RM, Weber E, Keana JF. Zhou ZL, et al. Among authors: woodward rm. Bioorg Med Chem. 2003 Apr 17;11(8):1769-80. doi: 10.1016/s0968-0896(03)00059-2. Bioorg Med Chem. 2003. PMID: 12659763

3

In vitro pharmacology of ACEA-1021 and ACEA-1031: systemically active quinoxalinediones with high affinity and selectivity for N-methyl-D-aspartate receptor glycine sites.

Woodward RM, Huettner JE, Guastella J, Keana JF, Weber E. Woodward RM, et al. Mol Pharmacol. 1995 Mar;47(3):568-81. Mol Pharmacol. 1995. PMID: 7700254

4

Blockade of morphine tolerance by ACEA-1328, a novel NMDA receptor/glycine site antagonist.

Lutfy K, Shen KZ, Kwon IS, Cai SX, Woodward RM, Keana JF, Weber E. Lutfy K, et al. Among authors: woodward rm. Eur J Pharmacol. 1995 Jan 24;273(1-2):187-9. doi: 10.1016/0014-2999(94)00716-k. Eur J Pharmacol. 1995. PMID: 7737313

5

Pharmacology of 5-chloro-7-trifluoromethyl-1,4-dihydro-2,3-quinoxalinedione: a novel systemically active ionotropic glutamate receptor antagonist.

Woodward RM, Huettner JE, Tran M, Guastella J, Keana JF, Weber E. Woodward RM, et al. J Pharmacol Exp Ther. 1995 Dec;275(3):1209-18. J Pharmacol Exp Ther. 1995. PMID: 8531083

6

Synthesis and structure-activity relationships of 1,2,3,4-tetrahydroquinoline-2,3,4-trione 3-oximes: novel and highly potent antagonists for NMDA receptor glycine site.

Cai SX, Zhou ZL, Huang JC, Whittemore ER, Egbuwoku ZO, Lü Y, Hawkinson JE, Woodward RM, Weber E, Keana JF. Cai SX, et al. Among authors: woodward rm. J Med Chem. 1996 Aug 16;39(17):3248-55. doi: 10.1021/jm960214k. J Med Chem. 1996. PMID: 8765507

7

Inhibition of morphine tolerance by NMDA receptor antagonists in the formalin test.

Lutfy K, Shen KZ, Woodward RM, Weber E. Lutfy K, et al. Among authors: woodward rm. Brain Res. 1996 Aug 26;731(1-2):171-81. doi: 10.1016/0006-8993(96)00469-6. Brain Res. 1996. PMID: 8883867

8

Pharmacology of ACEA-1416: a potent systemically active NMDA receptor glycine site antagonist.

Ilyin VI, Whittemore ER, Tran M, Shen KZ, Cai SX, Kher SM, Keana JF, Weber E, Woodward RM. Ilyin VI, et al. Among authors: woodward rm. Eur J Pharmacol. 1996 Aug 29;310(2-3):107-14. doi: 10.1016/0014-2999(96)00370-6. Eur J Pharmacol. 1996. PMID: 8884205

9

Analogs of 3-hydroxy-1H-1-benzazepine-2,5-dione: structure-activity relationship at N-methyl-D-aspartate receptor glycine sites.

Guzikowski AP, Cai SX, Espitia SA, Hawkinson JE, Huettner JE, Nogales DF, Tran M, Woodward RM, Weber E, Keana JF. Guzikowski AP, et al. Among authors: woodward rm. J Med Chem. 1996 Nov 8;39(23):4643-53. doi: 10.1021/jm960479z. J Med Chem. 1996. PMID: 8917653

10

Structure-activity relationships of 4-hydroxy-3-nitroquinolin-2(1H)-ones as novel antagonists at the glycine site of N-methyl-D-aspartate receptors.

Cai SX, Zhou ZL, Huang JC, Whittemore ER, Egbuwoku ZO, Hawkinson JE, Woodward RM, Weber E, Keana JF. Cai SX, et al. Among authors: woodward rm. J Med Chem. 1996 Nov 8;39(23):4682-6. doi: 10.1021/jm960520y. J Med Chem. 1996. PMID: 8917657

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